Results 51 to 60 of about 4,955 (173)

Fractionated Atrial Electrograms Identify Sites of Autonomic Responses During Pulmonary Vein Isolation: Insights for Cardioneuroablation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Conceptual overview of the study design and physiological rationale underlying programmable electrogram fractionation mapping during ablation. In the primary AF cohort, 27 predefined combinations of signal width, refractory period, and roving sensitivity were systematically evaluated across 870 ablation sites during PVI to identify electrogram ...
Juan F. Agudelo‐Uribe, Rafael Correa‐Velásquez, Juan D. Ramírez‐Barrera, Margarita Londoño‐Arango, Teresa Barrio‐López, Jesús Almendral   +5 more
wiley   +1 more source

Self-organization of blood pressure regulation: Clinical evidence

Frontiers in Physiology, 2016
The pathogenesis of vasovagal syncope has remained elusive despite many efforts to identify an underlying dysfunction. Catastrophe theory explains the spontaneous occurrence of sudden events in some mathematically complex systems known as self-organized ...
Jacques-Olivier eFortrat, claude egharib, claude egharib   +2 more
doaj   +1 more source

Safety considerations of gene‐based therapies for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Gene‐based therapies show increasing promise for the treatment of neurologic disease. In 2016, nusinersen, an RNA‐based therapy, was approved for children with spinal muscular atrophy (SMA). Over 200 clinical trials have utilized gene therapy approaches for a host of neurodegenerative and neuromuscular disorders, including Alzheimer's disease (
Elizabeth A. Bevins, Gabriel C. Léger, Michelle A. Herman, John M. Ringman, Subhojit Roy, Matthew Shtrahman, Judy Pa, Howard H. Feldman   +7 more
wiley   +1 more source

Iatrogenic Left Main Coronary Artery Dissection With Retrograde Aortic Extension During Complex Percutaneous Coronary Intervention in a Left‐Dominant System: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Clinical course of catheter‐induced left main coronary artery dissection during complex percutaneous coronary intervention (PCI) for heavily calcified left main bifurcation disease. Following iatrogenic ostial left main dissection with limited retrograde extension into the aortic root, immediate haemodynamic stabilisation and bailout PCI were performed
Ghulam Abbas Shaikh, Samina Yaqoob, Ali Aamir, Zahra Anas, Aniqa Dejwani, Atiqullah Sadaqat   +5 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, Volume 117, Issue 1, Page 24-41, July 2026.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Tilt Test as a Primary Non-Invasive Method for Testing Cardiac Autonomic Nervous System Function in Patients with Vasovagal Syncope

Український журнал серцево-судинної хірургії
Introduction Syncope is a sudden, brief loss of consciousness with rapid spontaneous recovery, caused by transient global cerebral hypoperfusion. Among various causes of syncope, the most common are reflex mechanisms, particularly vasovagal syncope ...
Dmytro A. Tymoshenko, Mykola V. Derkach, Alina V. Topchii   +2 more
doaj   +1 more source

Vasovagal oscillations and vasovagal responses produced by the Vestibulo-Sympathetic Reflex in the rat

Frontiers in Neurology, 2014
Sinusoidal galvanic vestibular stimulation (sGVS) induces oscillations in blood pressure (BP) and heart rate (HR) i.e., vasovagal oscillations, and decreases in BP and HR i.e., vasovagal responses, in isoflurane-anesthetized rats.
Sergei B. Yakushin, Giorgio eMartinelli, Theodore eRaphan, Yongqing eXiang, Gay R. Holstein, Gay R. Holstein, Bernard eCohen   +6 more
doaj   +1 more source

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, Volume 604, Issue 13, Page 5458-5492, 1 July 2026.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

Original paper
Heart rate variability in patients with recurrent syncope

Archives of Medical Science, 2006
Introduction: The autonomic nervous system participates in the pathophysiology of vasovagal syncope. The disturbances in the autonomic nervous system can be measured by heart rate variability (HRV).
Jan Henryk Goch, Małgorzata Lelonek
doaj  

Long QT Syndrome Type 5 With Coexisting KCNE1 and RYR2 Variants: A Diagnostic Ambiguity

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Long QT syndrome (LQTS) predisposes to syncope and sudden cardiac death. Type 5 LQTS, linked to KCNE1 variants, is rare. A teenage female presented with recurrent syncope. ECG showed QTc 485 ms. Genetic testing identified KCNE1 and RYR2 variants. Beta‐blockers and ICD prevented events.
Mohammad Hossein Nikoo, Hossein Fatemian, Amir Hossein Hassani, Mehrdad Rabiee Rad, Sara Mostafavi   +4 more
wiley   +1 more source