Results 91 to 100 of about 433,520 (307)
Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila
Advanced Science, EarlyView.Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu +7 more
wiley +1 more source
La subjecció a l’IVA de les biblioteques virtuals
IDP, 2011 Durant els últims anys les biblioteques virtuals han irromput amb força en el panorama educatiu i cultural espanyol i, en aquest sentit, s'han de reconèixer les mesures impulsores que s'han adoptat tant en l'àmbit nacional com en l'àmbit comunitari.
Lorenzo Gil Maciá
doaj +1 more source
The regressivity of a value added tax: tax credit method and subtraction method — a Japanese case [PDF]
Value added tax (VAT) is often described as a regressive tax because it taxes consumption, and the propensity to consume tends to decrease as income rises.
Masayuki Tamaoka
core
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Agricultural Economics (AGRICECON), 2009 The rules of the European Union suppose the value added tax as the only general excise tax. The need for harmonization of this tax in the existing EU member states is obvious, but the results in this field are not entirely convincing.
P. David
doaj +1 more source
The Turkish Journal of Thoracic and Cardiovascular SurgerySleeve resections in central tumors is a surgical method preferred over pneumonectomy owing to its parenchyma-sparing features. With the increasing surgical experience and developing technology in recent years, sleeve resections can be performed using the video-assisted thoracoscopic surgery method. However, these resections are technically challenging
Arkın, Acar, Kenan Can, Ceylan
openaire +2 more sources
Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Traceable Payments and VAT Design: Effects on VAT Performance
SSRN Electronic Journal, 2019 AbstractThis article studies the role of cashless payments in third-party reporting for the purposes of value-added tax (VAT) compliance management. In economies with well-developed financial institutions, the traceability of digital payments could serve as a deterrent to sales suppression even in the absence of explicit policies utilizing electronic ...
openaire +1 more source
An Implanted Tooth That Can Feel
Advanced Science, EarlyView.To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao +13 more
wiley +1 more source
Economic Effects of VAT Reform in Germany [PDF]
In the tax policy debate, differentiation of value-added taxes is often justified by distributional concerns. Our quantitative analysis for Germany indicates that such concerns are misplaced.
Boeters, Stefan +3 more
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