Results 111 to 120 of about 8,089 (264)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su   +4 more
wiley   +1 more source

Study of network composition in interpenetrating polymer networks of poly(N isopropylacrylamide) microgels:the role of poly(acrylic acid)

open access: yes, 2019
Hypothesis: The peculiar swelling behaviour of poly(N-isopropylacrylamide) (PNIPAM)-based responsive microgels provides the possibility to tune both softness and volume fraction with temperature, making these systems of great interest for technological ...
Angelini, Roberta   +7 more
core   +1 more source

Advancement in additive manufacturing & numerical modelling considerations of direct energy deposition process [PDF]

open access: yes, 2016
The development speed and application range of the additive manufacturing (AM) processes, such as selective laser melting (SLM), laser metal deposition (LMD) or laser-engineering net shaping (LENS), are ever-increasing in modern advanced manufacturing ...
Qin, Yi   +3 more
core   +1 more source

Energy Absorption Capacity of Bio-Inspired Honeycomb Integrated Beetle Elytron Plates

open access: yesEngineering Proceedings
Growth in the advancement of 3D printing technology has made it easy to fabricate complicated bio-inspired structures (BISs). In this paper, the sandwich structure of the beetle elytron structure (BES) hollow cylinder, influencing every corner of the ...
Ramakrishna Doodi   +3 more
doaj   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

open access: yesAdvanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui   +8 more
wiley   +1 more source

Innovative Hybrid Nanocomposites in 3D Printing for Functional Applications: A Review

open access: yesMolecules
3D printing has garnered significant attention across academia and industry due to its capability to design and fabricate complex architectures. Applications such as those requiring intricate geometries or custom designs, including footwear, healthcare ...
Nguyen Thi Kim Tuyen   +3 more
doaj   +1 more source

A new approach to vat polymerization additive manufacturing

open access: yes, 2022
Additive manufacturing and 3D Printing are getting more popular with the developments, inventions, and studies in design, material, and process technologies every day. As they get more popular, our lives change in our favor. However, there are still areas to be developed more and optimized.
openaire   +1 more source

Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials

open access: yesAdvanced Science, EarlyView.
Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon   +3 more
wiley   +1 more source

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