Results 191 to 200 of about 12,850,407 (289)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Regularized Joint Reconstruction and Slab Combination for Accelerated Three‐Dimensional Multi‐Slab Diffusion‐Weighted Imaging Using Multi‐Scale Energy Models

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To jointly reconstruct high‐resolution diffusion‐weighted volumes and eliminate slab‐boundary artifacts while preserving fine anatomical detail from undersampled 3D multi‐slab k‐space acquisitions. Methods A bilinear forward model was formulated to describe the 3D multi‐slab acquisition, treating the image volume and slab excitation ...
Reza Ghorbani   +4 more
wiley   +1 more source

The adiponectin/leptin ratio as a biomarker of adiposopathy and visceral adipose tissue accumulation: sex-specific mechanisms. [PDF]

open access: yesAdipocyte
Medina-Urrutia A   +10 more
europepmc   +1 more source

Myasthenia Gravis and Thymoma

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor   +5 more
wiley   +1 more source

Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation. [PDF]

open access: yesNat Commun
Vasamsetti SB   +18 more
europepmc   +1 more source

Otovent Versus Valsalva: Physiological Insights for Diagnostic and Therapeutic Autoinflation in Eustachian Tube Dysfunction

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Autoinflation aids assessment of Eustachian tube function, or as a conservative treatment for obstructive Eustachian tube dysfunction. This study compares the physiological characteristics of 2 autoinflation techniques, the Otovent® device and the Valsalva manoeuvre, to inform clinical application for both diagnosis and therapy ...
Kiran Joshi   +4 more
wiley   +1 more source

Muscle matters: automated CT-based body composition analysis predicts survival in patients with head and neck cancer treated with immunotherapy. [PDF]

open access: yesFront Oncol
Jungbauer F   +12 more
europepmc   +1 more source

Rethinking Public Administration Reform: Institutional Layering of Bureaucratic, Managerial and Community Logics Over Time in Nigeria's Tax Administration

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The reform of public institutions has attracted sustained attention in both scholarship and policymaking. Increasingly, however, there is growing recognition that reforms are rarely implemented in an institutional vacuum. Instead, new reforms are layered onto existing arrangements, producing hybrid institutional landscapes shaped by prior ...
Edidiong Bassey
wiley   +1 more source

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