Results 61 to 70 of about 61,958 (261)

Hormone-Like Effects of 4-Vinylcyclohexene Diepoxide on Follicular Development

open access: yesFrontiers in Cell and Developmental Biology, 2020
Background4-vinylcyclohexene diepoxide (VCD) has long been considered a hazardous occupational chemical that promotes ovarian failure. However, VCD is also used as a research compound to chemically induce animal models of premature ovarian insufficiency (
Lian Bao Cao   +39 more
doaj   +1 more source

Evaluation of Therapeutic Opioids in Skin‐Derived Matrices (Sweat and Sebum) of Neonatal and Pediatric Patients and Their Role in Opioid Incorporation Into Hair

open access: yesDrug Testing and Analysis, EarlyView.
Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke   +7 more
wiley   +1 more source

The in‐hospital administration of sacubitril/valsartan in acute myocardial infarction: A meta‐analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 998-1012, April 2025.
In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro   +15 more
wiley   +1 more source

A chiral rhenium complex with predicted high parity violation effects: synthesis, stereochemical characterization by VCD spectroscopy and quantum chemical calculations. [PDF]

open access: yesPhysical Chemistry, Chemical Physics - PCCP, 2013
With their rich electronic, vibrational, rotational and hyperfine structure, molecular systems have the potential to play a decisive role in precision tests of fundamental physics.
N. Saleh   +7 more
semanticscholar   +1 more source

Diselenide‐Catalyzed Asymmetric Allenylation of Alkynes

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
An asymmetric allenylation of alkynes is described using chiral lactamides‐based diselenides under oxidative conditions. This led to the corresponding allenylamides with enantiomeric excesses up to 72%, and uncovers an interesting stereodivergency feature related to the β‐H‐syn‐elimination of transient Se(IV) intermediates.
Rongyu Sun   +5 more
wiley   +1 more source

Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster

open access: yesRedox Biology, 2015
The compounds 4-vinylcyclohexene 1,2-monoepoxide (VCM) and 4-Vinylcyclohexene diepoxide (VCD) are the two downstream metabolites of 4-vinylcyclohexene (VCH), an ovotoxic agent in mammals.
Amos O. Abolaji   +6 more
doaj   +1 more source

Interpreting vibrational circular dichroism spectra: the Cai•factor for absolute configuration with confidence

open access: yesJournal of Cheminformatics, 2023
Vibrational circular dichroism (VCD) spectroscopy can generate the data required for the assignment of absolute configuration, but the spectra are hard to interpret.
Jonathan Lam   +2 more
doaj   +1 more source

Do Injury, Depression, and PTSD Mediate the Relationships Between Latent Profiles of Cumulative Lifetime Violence and Chronic Pain Disability in Men?

open access: yesResearch in Nursing &Health, EarlyView.
ABSTRACT Knowledge of association between violence and chronic pain in men is limited by neglect of violence experiences as perpetrator, disregard of heterogeneity in cumulative lifetime violence severity (CLVS), weak understanding of mediation pathways, and inattention to social determinants of health (SDOH).
Judith Wuest   +4 more
wiley   +1 more source

Prognostic Impact of the Hevylite Assay in Patients With IgG or IgA Multiple Myeloma Treated Within the GMMG-MM5 Trial. [PDF]

open access: yesEur J Haematol
ABSTRACT Response assessment during treatment of multiple myeloma (MM) typically relies on immunofixation and serum electrophoresis. However, low levels of IgG and especially IgA paraprotein are difficult to quantify reliably. The Hevylite Assay quantifies the kappa and lambda fractions of IgG and IgA separately and is useful to determine response to ...
Richardson T   +22 more
europepmc   +2 more sources

Substituent effect in theoretical VCD spectra

open access: yesRSC Adv., 2014
A correlational study shows for the first time a quantitative substituent effect on Vibrational Circular Dichroism intensity.
Piotr F. J. Lipiński   +1 more
openaire   +1 more source

Home - About - Disclaimer - Privacy