Results 181 to 190 of about 68,761 (259)

Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa, Shoko Miyoshi, Yuji Hayashi, Yuki Irifune, Eriko Sato, Sohei Mitani, Mohammed Choudhury, Hajime Yano, Junya Tanaka, Naohito Hato   +9 more
wiley   +1 more source

Evaluating the impact of the 'Four Pest-Free Villages' program on mosquito-borne disease control in Zhejiang Province, China: a cross-sectional study on knowledge, attitudes, and practices. [PDF]

Infect Dis Poverty
Ni J, Chen Q, Zhou H, Zhang W, Wang J, Sun J, Gong Z.   +6 more
europepmc   +1 more source

Skin models for studying vector-borne kinetoplastid infections

Current Opinion in Microbiology
Laura Hauf, Markus Engstler
openaire   +1 more source

Tick threats in the context of climate change: One Health response strategies in the Middle East and North Africa region. [PDF]

Sci One Health
Perveen N, Sparagano O, Gharbi M, Khan G, Qablan M, Iliashevich D, Kishore U, Willingham AL.   +7 more
europepmc   +1 more source

Multicentric longitudinal study on malaria burden, vector bionomics and health system assessment in diverse eco-epidemiological settings in the context of malaria elimination in India: study protocol. [PDF]

BMJ Open
Rahul A, Thiruvengadam K, Sharma R, Jabir M, Viswan A, Jency PJ, Bharadwaj N, Muthukumaravel S, Shriram AN, Raju HK, Kannan S, Singh M, Bhuyan PJ, Jain T, Rahi M.   +14 more
europepmc   +1 more source

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma

International Journal of Cancer, EarlyView.
What's New? Oncolytic viruses are a promising immunotherapeutic approach against many malignancies. However, it is unclear whether repeated doses have improved therapeutic value or may trigger greater side effects, especially in patients with hepatocellular carcinoma whose liver is chronically damaged.
Karen J. Scott, Emma J. West, Rebecca J. Brownlie, Fay Ismail, Christy Ralph, Thomas Heineman, Matt Coffey, Alan A. Melcher, Alison Taylor, Salvatore Papa, Adel Samson   +10 more
wiley   +1 more source

The Toxoplasma gondii prevalence and its impact on tick-borne encephalitis virus infection among humans in Heilongjiang province of China. [PDF]

Parasitol Res
Li W, Zhang L, Wang W, Yin W, Maimaiti F, Zhao M, Peng X, Wu W, Lv S, Hou Z.   +9 more
europepmc   +1 more source

Pyridoxal Reprograms Peroxisomal Hydrogen Peroxide Metabolism to Induce Lethal Oxidative Stress in Ovarian Cancer

iMetaMed, EarlyView.
Pyridoxal (PL) exhibits the strongest anti‐tumor activity within the vitamin B6 family, demonstrating significant ovarian cancer cell‐killing efficacy in vivo, in vitro, and in patient‐derived organoid (PDO) models. The anti‐tumor mechanism involves PL inducing a shift in peroxisome dynamics towards fission, promoting peroxisome proliferation, and ...
Ruonan Li, Huiyan Wang, Dunke Zhang, Qiuying Gu, Jinlong Wang, Bin Liu, Huabin Gao, Jingya Duan, Yimin Liu, Xiaolan Huang, Youquan Bu, Tongchuan He, Hua Linghu   +12 more
wiley   +1 more source

China's malaria elimination: One Health lessons for vector-borne disease governance. [PDF]

Biosaf Health
Liu J, Liu Y, Cheng G.
europepmc   +1 more source

CAT‐BLAST: Engineered bacteria for robust targeting and elimination of cancer‐associated fibroblasts

iMeta, EarlyView.
Cancer‐associated fibroblasts (CAFs) construct a protective stromal barrier that promotes tumor growth and resistance to therapy. To dismantle this, we developed CAT‐BLAST, an engineered bacterial platform designed to potently eliminate these cells. We engineered a safe, high‐expression E.
Mengdi Xu, Ehsan Hashemi, Hui Gao, Qumar Zaman, Yi Ma, Jufang Wang, Wenjun Mao, Zhuobin Liang   +7 more
wiley   +1 more source