Results 31 to 40 of about 122,214 (202)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A note on set-valued Henstock--McShane integral in Banach (lattice) space setting [PDF]
, 2015 We study Henstock-type integrals for functions defined in a Radon measure space and taking values in a Banach lattice $X$. Both the single-valued case and the multivalued one are considered (in the last case mainly $cwk(X)$-valued mappings are discussed).
Boccuto, Antonio +2 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
What is perfect competition? [PDF]
, 1990 Includes bibliographical references (p. 38-39)
Rustichini, Aldo, Yannelis, Nicholas C.
core
Asymptotic Spectral Measures, Quantum Mechanics, and E-theory
, 2001 We study the relationship between POV-measures in quantum theory and asymptotic morphisms in the operator algebra E-theory of Connes-Higson. This is done by introducing the theory of "asymptotic" PV-measures and their integral correspondence with ...
Martinez, Diane, Trout, Jody
core +4 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
$L^p$ spaces in vector lattices and applications
, 2016 $L^p$ spaces are investigated for vector lattice-valued functions, with respect to filter convergence. As applications, some classical inequalities are extended to the vector lattice context, and some properties of the Brownian Motion and the Brownian ...
Boccuto, Antonio +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source