Results 141 to 150 of about 2,392,273 (315)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Blood Parasites (Haemosporida, Trypanosomatida) in Culex pipiens: A Study and Review of Hibernating and Active Mosquitoes

Microbiology Research
Culex pipiens mosquitoes (Diptera: Culicidae) are widespread during warm periods and actively feed on blood while serving as vectors for various human and animal pathogens. Culex mosquitoes overwinter as adults in temperate zones, raising the question of
Kristina Valavičiūtė-Pocienė, Margarita Kazak, Tatjana Iezhova, Gabrielė Kalinauskaitė, Rasa Bernotienė   +4 more
doaj   +1 more source

Hiding the Vector Resonance Signal Hiding the Vector Resonance Signal

, 2014
We investigate how the interplay of the direct and mixing-induced couplings of the hypothetical SU(2)L+R vector triplet resonance to the third quark generation can hide the resonance signal in ,tb tb , and / bt tb channels.
Mikulas Gintner, Josef Juran
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Gene Therapy for Glioblastoma Multiforme

Viruses
Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor patient outcomes and a five-year survival of less than 10%. Significant limitations to effective GBM treatment include poor drug delivery across the blood–brain ...
Smit Shah, Joshua Green, Shantelle A. Graff, Qi Li, John D. Heiss   +4 more
doaj   +1 more source

A Modified Vector Space Model For Protein Retrieval. [PDF]

, 2007
This paper provides an enhancement of an existing method of information retrieval which is a modification of Vector Space Model for information retrieval.
Abdul Rashid, Nur'Aini, Abdullah, Rosni, Abual-Rub, Mohammed Said   +2 more
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Effects of Climatic, Chemical, and Cultural Control Strategies on Community Composition of Auchenorrhyncha and Population Dynamics of Two Major Green Leafhopper Pests in Peach Orchards

Agronomy
A three-year study in two Mediterranean peach orchards monitored Auchenorrhyncha species, including the main vectors of plant pathogens causing significant economic losses.
Patrícia Monteiro Nascimento, Ana Carina Neto, Vera Guerreiro, Anabela Barateiro, Hugo Anjos, José Pereira Coutinho, Marília Antunes, Maria Teresa Rebelo   +7 more
doaj   +1 more source

Massive Data Classification via Unconstrained Support Vector Machines

, 2006
A highly accurate algorithm, based on support vector machines formulated as linear programs [13, 1], is proposed here as a completely unconstrained minimization problem [15].
O. L. Mangasarian, Mangasarian, Olvi, Thompson, Michael, M. E. Thompson   +3 more
core   +1 more source