Results 21 to 30 of about 1,674,962 (266)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A permanental vector is a generalization of a vector with components that are squares of the components of a Gaussian vector, in the sense that the matrix that appears in the Laplace transform of the vector of Gaussian squares is not required to be either symmetric or positive definite.
Kogan, Hana, Marcus, Michael B.
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Callus molding in external and internal distraction of mandible
Background: Distraction osteogenesis (DO) emerges to be a promising alternative to the traditional method of bone lengthening, by which a significant skeletal and soft tissue enlargement can be obtained in the hypoplastic area in a short period ...
S M Balaji
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
THE ASSESSMENT OF THE AMOUNT OF SOLID PARTICLES IN THE SEDIMENTARY TANKS AND THEIR EFFLUENT [PDF]
When a stochastic state space model of a given system is formulated and measurements from thesystem are obtained, the parameters are to be estimated. Even though different approaches to the estimationproblem are described in the literature (LJUNG, 1999),
Valeria Victoria IOVANOV
doaj
The main purpose of this paper is to study the vector groupoids. This is an algebraic structure which combines the concepts of Brandt groupoid and vector space such that these are compatible.
Popuţa, Vasile, Ivan, Gheorghe
openaire +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Coccidian (Apicomplexa: Coccidia) parasites have been reported in almost all groups of vertebrates. These parasites may cause serious ecological and pathological effects to their hosts.
Hossein Javanbakht, Reyhaneh Hajian
doaj
Performance Testing on Vector vs. Raster Map Tiles—Comparative Study on Load Metrics
Recent developments in web map applications have widely affected how background maps are rendered. Raster tiles are currently considered as a regular solution, while the use of vector tiles is becoming more widespread.
Rostislav Netek +3 more
doaj +1 more source

