Results 31 to 40 of about 219,381 (279)
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Real Hypersurfaces of Type A in Complex Two-Plane Grassmannians Related to The Reeb Vector Field
, 2015 Y. J. Suh and H. Lee (Bull. Korean. Math. Soc. 47, 551-561 (2010)) characterized real hypersurfaces $M$ of type $B$ by the invariance of vector bundle $JTM^\perp$ under the shape operator and the orthogonality of $JTM^\perp$ and $\mathcal {J}TM^\perp ...
Lee, Ruenn-Huah, Loo, Tee-How
core +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Моделирование и анализ информационных систем, 2015 A linear projective ind-variety X is called 1-connected if any two points on it can be connected by a chain of lines l1, l2, ..., lk in X, such that li intersects li+1.
S. M. Yermakova
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Fiber-Preserving Conformal Vector Field of Frame Bundles with Natural Riemannian Metric [PDF]
Memoirs of the Scientific Sections of the Romanian Academy, 2019 We consider the bundle of all oriented orthonormal frames over an orientable Remannian manifold. This bundle has a natural Riemannian metric which is defined by the Riemannian connection of the base manifold.
M.T.K. Abbassi , N. Amri
doaj
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Higher order jet prolongations type gauge natural bundles over vector bundles
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2004 Let $rgeq 3$ and $mgeq 2$ be natural numbers and $E$ be a vector bundle with $m$-dimensional basis. We find all gauge natural bundles ``similar" to the $r$-jet prolongation bundle $J^rE$ of $E$.
Jan Kurek, Włodzimierz M. Mikulski
doaj
Vector bundles of rank four and A_3 = D_3
, 2012 Over a scheme with 2 invertible, we show that a vector bundle of rank four has a sub or quotient line bundle if and only if the canonical symmetric bilinear form on its exterior square has a lagrangian subspace.
Asher Auel +32 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source