Results 121 to 130 of about 1,936,574 (368)

Turning vector bundles

open access: yesAlgebraic & Geometric Topology
We define a turning of a rank-$2k$ vector bundle $E \to B$ to be a homotopy of bundle automorphisms $ψ_t$ from $\mathbb{Id}_E$, the identity of $E$, to $-\mathbb{Id}_E$, minus the identity, and call a pair $(E, ψ_t)$ a turned bundle. We investigate when vector bundles admit turnings and develop the theory of turnings and their obstructions.
Crowley, Diarmuid   +3 more
openaire   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Seshadri constants for vector bundles [PDF]

open access: yesJournal of Pure and Applied Algebra, 2019
Mihai Fulger, T. Murayama
semanticscholar   +1 more source

Higher Vector Bundles

open access: yesInternational Mathematics Research Notices
Abstract We introduce higher analogs for cleavages in the context of (Kan) simplicial fibrations. We apply them to obtain geometric models for representations up to homotopy of (higher) Lie groupoids. Concretely, we set an equivalence between representations up to homotopy and simplicial vector bundles endowed with a cleavage. Our result
del Hoyo, Matias, Trentinaglia, Giorgio
openaire   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The extended vector bundles

open access: yesJournal of Geometry, 1998
In this study, the structure of extended vector bundles has been obtained, especially the canonical extended vector bundle πk of order k of any vector bundle π=(E,π,M). © Birkhäuser Verlag, 1998.
openaire   +4 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

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