Results 41 to 50 of about 162,218 (329)

K-theory and phase transitions at high energies

Pracì Mìžnarodnogo Geometričnogo Centru, 2016
The duality between E8xE8 heteritic string on manifold K3xT2 and Type IIA string compactified on a Calabi-Yau manifold induces a correspondence between vector bundles on K3xT2 and Calabi-Yau manifolds.
T. V. Obikhod
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Nefness of adjoint bundles for ample vector bundles

Le Matematiche, 1995
Let E be an ample vector bundle of rank >1 on a smooth complex projective variety X of dimension n. This paper gives a classification of pairs (X,E) whose adjoint bundles K_X+det E are not nef in the case when  r=n-2.
Hidetoshi Maeda
doaj  

Moduli Stacks of Vector Bundles and Frobenius Morphisms

, 2004
We describe the action of the different Frobenius morphisms on the cohomology ring of the moduli stack of algebraic vector bundles of fixed rank and determinant on an algebraic curve over a finite field in characteristic p and analyse special situations ...
A Beauville, C Teleman, D Gaitsgory, D Mumford, E Bifet, G Faltings, G Faltings, G Harder, G Laumon, H Lange, J Heinloth, K Joshi, KA Behrend, M Artin, MF Atiyah, MS Ragunathan, P Deligne, S Kumar, V Drinfeld, Y Laszlo, Y Laszlo   +20 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

On lifts of symplectic vector bundles and connections to Weil bundles

Extracta Mathematicae
In this paper, we generalize to Frobenius-Weil bundles some lifts of symplectic manifolds and symplectic vector bundles.
E. Hinamari Mang-massou, A. Ntyam
doaj   +1 more source

Formation of high-order cylindrical vector beams with sector sandwich structures

Компьютерная оптика, 2022
Complex polarization-phase transformations are considered, which are implemented using easy-to-manufacture optical elements. The manufacturing technology of such elements is based on the axially symmetric discretization of the required polarization and ...
S.V. Karpeev, V.V. Podlipnov, S.A. Degtyarev, A.M. Algubili   +3 more
doaj   +1 more source

Globally generated vector bundles on a smooth quadric surface

, 2014
We give the classification of globally generated vector bundles of rank $2$ on a smooth quadric surface with $c_1\le (2,2)$ in terms of the indices of the bundles, and extend the result to arbitrary higher rank case.
Ballico, Edoardo, Huh, Sukmoon, Malaspina, Francesco   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source