Results 81 to 90 of about 14,865,566 (335)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
On $g$-natural conformal vector fields on unit tangent bundles [PDF]
, 2021 summary:We study conformal and Killing vector fields on the unit tangent bundle, over a Riemannian manifold, equipped with an arbitrary pseudo-Riemannian $g$-natural metric.
Amri, Noura +1 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Orbital Reversibility of Planar Vector Fields
Mathematics, 2020 In this work we use the normal form theory to establish an algorithm to determine if a planar vector field is orbitally reversible. In previous works only algorithms to determine the reversibility and conjugate reversibility have been given.
Antonio Algaba +2 more
doaj +1 more source
Nil-Killing vector fields and Kundt structures [PDF]
, 2020 This thesis is based on three papers, for which two have been submitted for publication and one is published. A chapter presenting relevant background material is included giving convenient access to preliminary foreknowledge for the papers. The research
Aadne, Matthew Terje
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Vector fields on nonorientable surfaces
International Journal of Mathematics and Mathematical Sciences, 2003 A one-to-one correspondence is established between the germs of functions and tangent vectors on a NOS X and the bi-germs of functions, respectively, elementary fields of tangent vectors (EFTV) on the orientable double cover of X.
Ilie Barza, Dorin Ghisa
doaj +1 more source
Fixed Points of Local Actions of Lie Groups on Real and Complex 2-Manifolds
Axioms, 2015 I discuss old and new results on fixed points of local actions by Lie groups G on real and complex 2-manifolds, and zero sets of Lie algebras of vector fields. Results of E. Lima, J. Plante and C. Bonatti are reviewed.
Morris W. Hirsch
doaj +1 more source
Spatiospectral concentration of vector fields on a sphere [PDF]
, 2013 We construct spherical vector bases that are bandlimited and spatially concentrated, or, alternatively, spacelimited and spectrally concentrated, suitable for the analysis and representation of real-valued vector fields on the surface of the unit sphere,
A. Plattner, F. Simons
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source