Results 71 to 80 of about 359,834 (262)

Malaria prevention practices among mothers delivering in an urban hospital in southwest Nigeria [PDF]

Journal of Vector Borne Diseases, 2008
Background & objectives: The pregnant woman is more prone to malaria than her non-pregnant counterpart with grave consequences for both mother and baby.
O.B. Yusuf, H.O. Dada-Adegbola, I.O. Ajayi, C.O. Falade   +3 more
doaj  

The importance of being urgent: The impact of surveillance target and scale on mosquito-borne disease control

Epidemics, 2018
With the emergence or re-emergence of numerous mosquito-borne diseases in recent years, effective methods for emergency vector control responses are necessary to reduce human infections.
Samantha R. Schwab, Chris M. Stone, Dina M. Fonseca, Nina H. Fefferman   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Criteria for Closedness of Vector Measures [PDF]

Proceedings of the American Mathematical Society, 1984
It is shown that there is a large class of locally convex spaces, which includes, for example, all spaces which are metrizable or Suslin or have the strict Mackey convergence property as well as many dual spaces, with the property that any vector measure assuming its values in such a space is a closed measure.
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Vector measures: where are their integrals?

Positivity, 2008
Let ν be a vector measure with values in a Banach space Z. The integration map Iν:L1(ν)→Z, given by f↦∫fdν for f ∈ L 1(ν), always has a formal extension to its bidual operator I∗∗ν:L1(ν)∗∗→Z∗∗. So, we may consider the “integral” of any element f ** of L 1(ν)** as I **ν(f **). Our aim is to identify when these integrals lie in more tractable subspaces Y
Curbera, Guillermo, Delgado, Olvido, Ricker, Werner J.   +2 more
openaire   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Stability Analysis and Optimal Control of a Vector-Borne Disease with Nonlinear Incidence

Discrete Dynamics in Nature and Society, 2012
The paper considers a model for the transmission dynamics of a vector-borne disease with nonlinear incidence rate. It is proved that the global dynamics of the disease are completely determined by the basic reproduction number.
Muhammad Ozair, Abid Ali Lashari, Il Hyo Jung, Kazeem Oare Okosun   +3 more
doaj   +1 more source

Vector Measures on Topological Spaces [PDF]

gmj, 2007
Abstract Let 𝑋 be a completely regular Hausdorff space, 𝐸 a quasi-complete locally convex space, 𝐶(𝑋) (resp. 𝐶𝑏(𝑋)) the space of all (resp. all, bounded), scalar-valued continuous functions on 𝑋, and 𝐵(𝑋) and 𝐵0(𝑋) be the classes of Borel and Baire subsets of 𝑋.
openaire   +2 more sources