Results 181 to 190 of about 8,579,021 (292)
Multifunctional multiphysics metamaterials via decomposition-based multiobjective optimization design. [PDF]
Chen Z +6 more
europepmc +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
JAX-AMG: A GPU-accelerated differentiable sparse linear solver library for JAX. [PDF]
Liu Y, Fan X, Wang JX.
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Multi-Morphogen Fields and Homeostatic Resource Allocation for Constrained Multiobjective Evolutionary Optimization. [PDF]
Chen X, Li Y, Li X, Yang Y.
europepmc +1 more source
Low‐dose electron holography is limited by shot noise, which buries weak phase signals. HoloDenoiser, a physics‐informed network that works simultaneously in the spatial and frequency domains, locates and protects the holographic sideband while suppressing noise in the hologram.
Ye Luo +10 more
wiley +1 more source
AOO-ANFIS: A Novel Bio-Inspired Neuro-Fuzzy Controller for Hydrostatic Transmission Stroke Control. [PDF]
Ülker H.
europepmc +1 more source
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source
Towards Autonomous Bio-Inspired Optimization: Deep Reinforcement Learning for Adaptive Metaheuristic Orchestration. [PDF]
Carrasco C +5 more
europepmc +1 more source
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang +10 more
wiley +1 more source

