Results 31 to 40 of about 417,841 (308)

On the Vector in Homogeneous Spaces [PDF]

open access: yesNagoya Mathematical Journal, 1953
The main purpose of this paper is to investigate the parallelism of vectors in homogeneous spaces. The definition of a vector and the condition for spaces under which a covariant differential of a vector is also a vector were given by E. Cartan [4] in a very intuitive way. Here I formulate this in a stricter way by his method of moving frame. Even if a
openaire   +3 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

A DIFFERENTIABLE STRUCTURE ON A FINITE DIMENSIONAL REAL VECTOR SPACE AS A MANIFOLD

open access: yesBarekeng, 2023
There are three conditions for a topological space to be said a topological manifold of dimension  : Hausdorff space, second-countable, and the existence of homeomorphism of a neighborhood of each point to an open subset of  or -dimensional locally ...
Edi Kurniadi
doaj   +1 more source

MADNESS IN VECTOR SPACES [PDF]

open access: yesThe Journal of Symbolic Logic, 2019
AbstractWe consider maximal almost disjoint families of block subspaces of countable vector spaces, focusing on questions of their size and definability. We prove that the minimum infinite cardinality of such a family cannot be decided in ZFC and that the “spectrum” of cardinalities of mad families of subspaces can be made arbitrarily large, in analogy
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Hierarchical and Non-Hierarchical Linear and Non-Linear Clustering Methods to “Shakespeare Authorship Question”

open access: yesSocial Sciences, 2015
A few literary scholars have long claimed that Shakespeare did not write some of his best plays (history plays and tragedies) and proposed at one time or another various suspect authorship candidates. Most modern-day scholars of Shakespeare have rejected
Refat Aljumily
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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