Results 41 to 50 of about 413,476 (255)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On Linear Algebra Education [PDF]
Linear algebra is a basic course followed in mathematics, science, and engineering university departments.Generally, this course is taken in either the first or second year but there have been difficulties in teachingand learning.
Sinan AYDIN
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Design of Partial Mueller-Matrix Polarimeters for Application-Specific Sensors
At a particular frequency, most materials and objects of interest exhibit a polarization signature, or Mueller matrix, of limited dimensionality, with many matrix elements either negligibly small or redundant due to symmetry.
Brian G. Hoover, Martha Y. Takane
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Lattices Constructions for Euclidean Space Rn and its Subspaces
A lattice is a discrete subgroup of n-dimensional Euclidean space that serves as a fundamental object of study in Algebra and the Geometry of Numbers.
Zahira Najmatul Hayyah +2 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Asymmetrical Six-Phase Space Vector Pwm Scheme
Multiphase electric motors have smaller torque pulsations and are more reliable that their three-phase alternatives. However, standard electricity grids around the world are three-phase, so power inverter is needed to drive multiphase motors. Inverter is
Tadas Lipinskis
doaj +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source

