Results 51 to 60 of about 2,467,001 (317)

Conventional Space-Vector Modulation Techniques versus the Single-Phase Modulator for Multilevel Converters [PDF]

open access: yes, 2010
Space-vector modulation is a well-suited technique to be applied to multilevel converters and is an important research focus in the last 25 years. Recently, a single-phase multilevel modulator has been introduced showing its conceptual simplicity and
Carrasco Solís, Juan Manuel   +6 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Vectorial Formalism of Polyphase Synchronous Machine With Permanents Magnets

open access: yesAceh International Journal of Science and Technology, 2013
This paper presents a mathematical model that transforms the real machine to fictitious machines and our goal is to simulate these and see the behavior of these machines in load.
Nacéra Bachir Bouiadjra   +6 more
doaj  

The Canonical Lattice Isomorphism between Topologies Compatible with a Linear Space

open access: yes, 2020
We consider all compatible topologies of an arbitrary finite-dimensional vector space over a non-trivial valuation field whose metric completion is a locally compact space.
Aoyama, Takanobu
core  

Vector fields on mapping spaces and a converse to the AKSZ construction [PDF]

open access: yes, 2012
The well-known AKSZ construction (for Alexandrov--Kontsevich--Schwarz--Zaboronsky) gives an odd symplectic structure on a space of maps together with a functional $S$ that is automatically a solution for the classical master equation $(S,S)=0$. The input
Voronov, Theodore Th.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Spin vector control of a spinning space station [PDF]

open access: yes, 1971
Digital computer program simulates system and related functions. Program is intended for, but not limited to, altitude control studies of rotating space station.
Hendricks, T.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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