Results 31 to 40 of about 8,456 (309)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Research on Yaw Moment Control System for Race Cars Using Drive and Brake Torques
Vehicles, 2023 The yaw acceleration required for circuit driving is determined by the time variation of the yaw rate due to two factors: corner radius and velocity at the center of gravity. Torque vectoring systems have the advantage where the yaw moment can be changed
Ikkei Kobayashi +9 more
doaj +1 more source
Performance Improvement of Sparse Matrix Vector Product on Vector Machines [PDF]
, 2006 Many applications based on finite element and finite difference methods include the solution of large sparse linear systems using preconditioned iterative methods. Matrix vector multiplication is one of the key operations that has a significant impact on the performance of any iterative solver.
Sunil R. Tiyyagura +2 more
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Fluidic Vectoring of a Planar Incompressible Jet Flow
EPJ Web of Conferences, 2018 This paper presents an experimental, a numerical and a theoretical analysis of the performances of a fluidic vectoring device for controlling the direction of a turbulent, bi-dimensional and low Mach number (incompressible) jet flow.
Mendez Miguel Alfonso +3 more
doaj +1 more source
The Sub-Band Vectoring Technique for Multi-Operator Environments
IEEE Access, 2016 Self- and alien-far end cross talk (FEXT) disturbances on the same cable severely limit performance in the commonly employed VDSL2 17a (0 - 17.6 MHz) standard profile.
Francesco Vatalaro +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Numerical Analysis of Bypass Mass Injection on Thrust Vectoring of Supersonic Nozzle
MATEC Web of Conferences, 2018 High speed aerospace applications require rapid control of thrust (i.e. thrust vectoring) in order to achieve better manoeuvrability. Among the existing technologies, shock vector control is one of the efficient ways to achieve thrust vectoring.
Islam Md Shafiqul +2 more
doaj +1 more source
Numerical investigation of freestream flow effects on thrust vector control performance
Ain Shams Engineering Journal, 2018 The current research attempted to apply a numerical investigation for external freestream-flow influence on thrust-vector control. The freestream-flow Mach numbers varying from 0.05 to 1.1 were studied at different flow conditions. Computational modeling
Farzad Forghany +2 more
doaj +1 more source