Results 131 to 140 of about 10,499 (305)
Presently, the exponential growth of unstructured data on the web and social networks has made it increasingly challenging for individuals to retrieve relevant information efficiently.
Jyotirmayee Rautaray +4 more
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Topology preserving vectorization
An approach to the automatic vectorization of binary raster images is presented, which combines the topology of the image contents and the shape of the image lines into a single representation.
Stork, A., Madeira, J.
core
In recent years, optimizing classification pipelines has become increasingly critical due to the growing volume of textual data and the computational challenges associated with exhaustive hyperparameter tuning.
Fernando Rezende Zagatti +3 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Vectorization of raster data using thining algorithm.
Until the early 1980`s, computer graphics was a small, specialized field, largely because the hardware was expensive and graphics-based application programs that were easy to use and cost effective-were few.
Velutis, Vaidas,
core
Parallelization and vectorization of ROOT fitting classes
We introduce parallelization and vectorization in ROOT mathematical and statistical libraries in order to take full advantage of new computer architectures and to maximize the CPU usage with an increasing amount of data to analyze. As part of this effort,
Valls Pla, X, Moneta, L
core +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source

