Results 21 to 30 of about 1,058,840 (250)

Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms

EvoDevo, 2018
Background Tapeworms are agents of neglected tropical diseases responsible for significant health problems and economic loss. They also exhibit adaptations to a parasitic lifestyle that confound comparisons of their development with other animals ...
Peter D. Olson, Magdalena Zarowiecki, Katherine James, Andrew Baillie, Georgie Bartl, Phil Burchell, Azita Chellappoo, Francesca Jarero, Li Ying Tan, Nancy Holroyd, Matt Berriman   +10 more
doaj   +1 more source

Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines

Vaccines, 2022
New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce its severity, the development of
Zeyu Yang, Xingge Xu, Cristina A. T. Silva, Omar Farnos, Alina Venereo-Sanchez, Cécile Toussaint, Shantoshini Dash, Irene González-Domínguez, Alice Bernier, Olivier Henry, Amine Kamen   +10 more
doaj   +1 more source

Sialotranscriptomics of Rhipicephalus zambeziensis reveals intricate expression profiles of secretory proteins and suggests tight temporal transcriptional regulation during blood-feeding

Parasites & Vectors, 2017
Background Ticks secrete a diverse mixture of secretory proteins into the host to evade its immune response and facilitate blood-feeding, making secretory proteins attractive targets for the production of recombinant anti-tick vaccines.
Minique Hilda de Castro, Daniel de Klerk, Ronel Pienaar, D Jasper G Rees, Ben J Mans   +4 more
doaj   +1 more source

The influence of temperature and humidity on the flight activity of Culicoides imicola both under laboratory and field conditions

Parasites & Vectors, 2019
Background Insight into the factors that regulate the circadian host-seeking flight activity of Culicoides vectors (Diptera: Ceratopogonidae) will be of importance to assess the risk of transmission of Culicoides-borne pathogens.
Gert J. Venter, Solomon N. B. Boikanyo, Chantel J. de Beer   +2 more
doaj   +1 more source

The first detected airline introductions of yellow fever mosquitoes (Aedes aegypti) to Europe, at Schiphol International airport, the Netherlands

Parasites & Vectors, 2017
Background Air-borne introduction of exotic mosquitoes to Schiphol airport in the Netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011.
A. Ibañez-Justicia, A. Gloria-Soria, W. den Hartog, M. Dik, F. Jacobs, A. Stroo   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Tropism-modification strategies for targeted gene delivery using adenoviral vectors [PDF]

, 2010
Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ...
Coughlan, L., Raul Alba, Coughlan, Lynda, Mcneish, I.A., Andrew H. Baker, Iain A. McNeish, Alba, R., Lynda Coughlan, Parker, Alan L., Nicklin, Stuart A., Bradshaw, Angela C., Bradshaw, A.C., Nicklin, S., Angela C. Bradshaw, Alan L. Parker, Stuart A. Nicklin, McNeish, Iain A., Baker, Andrew H., Parker, A.L., Alba, Raul, Baker, A.   +20 more
core   +1 more source

Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum

Epigenetics & Chromatin
Background Anopheles mosquitoes and the malaria parasites they transmit remain a significant global health problem. Most genomic and functional genomic studies of mosquitoes have focused on the protein-coding genome, and comparatively little is known ...
Natalia Marta Zmarlak-Feher, Kathryn S. Taquet, Renée Zakhia, Adrien Pain, Emma Brito-Fravallo, Cameron E. Anderson, Kenneth D. Vernick, Christian Mitri, Michelle M. Riehle   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Nationwide surveillance detects yellow fever and chikungunya viruses in multiple Aedes mosquito species in Nigeria

Parasites & Vectors
Background Since the reemergence of yellow fever in 2017, the Nigeria Centre for Disease Control (NCDC) has been coordinating responses to local outbreaks with the support of the World Health Organization (WHO).
Udoka C. Nwangwu, Harouna Soumare, Judith U. Oguzie, William E. Nwachukwu, Cosmas O. Onwude, Festus A. Dogunro, Mawlouth Diallo, Chukwuebuka K. Ezihe, Nneka O. Agashi, Emelda I. Eloy, Stephen O. Anokwu, Clementina C. Anioke, Linda C. Ikechukwu, Chukwuebuka M. Nwosu, Oscar N. Nwaogo, Ifeoma M. Ngwu, Rose N. Onyeanusi, Angela I. Okoronkwo, Francis U. Orizu, Monica O. Etiki, Esther N. Onuora, Peter C. Okeke, Okechukwu C. Chukwuekezie, Josephine C. Ochu, Anise N. Happi, Sulaiman S. Ibrahim, Adetifa Ifedayo, Chikwe Ihekweazu, Christian T. Happi   +28 more
doaj   +1 more source