Effect of Low Dose Intravenous Dexmedetomidine with 4% Sevoflurane on Haemodynamic Response during Laryngoscopy and Tracheal Intubation: A Randomised Controlled Study [PDF]
Introduction: Over the last decade, the use of dexmedetomidine has found favour in obtunding the haemodynamic response during laryngoscopy and tracheal intubation but the use of higher doses has lead to a number of adverse effects.
Maninder Kaur, Sargam Goel
doaj +1 more source
Mydriasis in eastern box turtles (Terrapene carolina carolina) following topical administration of proparacaine, 10% phenylephrine, and rocuronium bromide. [PDF]
Abstract Objective To determine the mydriatic effect of topical 10% phenylephrine with 10 mg/mL rocuronium bromide and compare this protocol with and without pretreatment with proparacaine. Animals Studied Ten client‐owned pet adult eastern box turtles (Terrapene carolina carolina).
Tucker-Retter EK +2 more
europepmc +2 more sources
The Histone Deacetylase Activator ITSA-1 Improves the Prognosis of Cardiac Arrest Rats by Alleviating Systemic Inflammatory Responses Following Cardiopulmonary Resuscitation. [PDF]
Objective: To investigate whether the histone deacetylase (HDAC) activator ITSA‐1 can ameliorate systemic inflammation after cardiac arrest (CA), thereby enhancing cardiac function and neurological outcomes in rats. Materials and Methods: Sixty‐nine healthy adult male Wistar rats were subjected to 12 min of CA induced by Vecuronium bromide.
Zhang C +11 more
europepmc +2 more sources
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J +2 more
core +2 more sources
Background and Aims: Previous studies suggest that administration of vecuronium based on total body weight rather than ideal body weight (IBW) in obesity results in overdosing with prolonged recovery times.
Satyen Parida +3 more
doaj +1 more source
Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape +46 more
core +1 more source
Establishment of a nonshockable rhythm cardiac arrest model caused by asphyxia
Objective Cardiac arrest (CA) is caused by a nonshockable rhythm with a low success rate of return of spontaneous circulation (ROSC) and a poor prognosis. This study intended to establish a nonshockable rhythm CA model caused by asphyxia.
Chenyu Zhang +7 more
doaj +1 more source
Reversal of Pipecuronium-Induced Moderate Neuromuscular Block with Sugammadex in the Presence of a Sevoflurane Anesthetic: A Randomized Trial [PDF]
BACKGROUND: Pipecuronium is a steroidal neuromuscular blocking agent. Sugammadex, a relaxant binding [gamma]-cyclodextrin derivative, reverses the effect of rocuronium, vecuronium, and pancuronium.
Asztalos, László +5 more
core +1 more source
The pharmacological treatment of epilepsy in adults
Abstract The pharmacological treatment of epilepsy entails several critical decisions that need to be based on an individual careful risk–benefit analysis. These include when to initiate treatment and with which antiseizure medication (ASM). With more than 25 ASMs on the market, physicians have opportunities to tailor the treatment to individual ...
Torbjörn Tomson +3 more
wiley +1 more source
Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium. [PDF]
Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia.
Aldasoro Celaya, Martín +10 more
core +1 more source

