Results 51 to 60 of about 177,179 (246)

A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing [PDF]

, 2008
Acid-sensitive K+ channels of the tandem P-domain K+-channel family (TASK-1 and TASK-3) have been implicated in peripheral and central respiratory chemosensitivity; however, because of the lack of decisive pharmacological agents, the final proof of the ...
Gourine, A. V., Isabel Aller, M., Trapp, S., Wisden, W.   +3 more
core   +1 more source

Bosutinib mitigates inflammation in experimental sepsis

European Journal of Clinical Investigation, Volume 55, Issue 9, September 2025.
Abstract Background Sepsis, a leading cause of death globally, lacks targeted and effective treatment. Its pathophysiology involves unbalanced inflammation, marked by a high release of inflammatory mediators, leukocyte recruitment, vascular changes and dysfunction of the nervous and respiratory systems. Src family tyrosine kinases (SFK) play a critical
C. M. C. Cunha, V. H. P. Abreu, V. Estato, G. M. V. Soares, B. P. T. Moraes, G. P. Oliveira, J. D. Silva, P. L. Silva, R. Immler, P. R. Rocco, M. Sperandio, A. R. Silva, P. T. Bozza, H. C. Castro‐Faria‐Neto, C. F. Gonçalves‐de‐Albuquerque   +14 more
wiley   +1 more source

A comparative study to evaluate the optimum intubating dose of rocuronium bromide versus succinylcholine chloride as an ideal intubating muscle-relaxing agent

Asian Journal of Medical Sciences
Background: Rocuronium bromide is a new amino steroidal neuromuscular blocking agent which is structurally related to vecuronium and its onset time and intubating conditions are comparable with succinylcholine and without the undesirable side effects.
Pratibha Bhunia , Anupama Mandal , Subhrangsu Chatterjee , Nairita Mayur   +3 more
doaj   +1 more source

Postoperative pain after MiniLap percutaneous versus standard laparoscopic salpingo‐oophorectomy: A propensity‐matched study

International Journal of Gynecology &Obstetrics, Volume 170, Issue 2, Page 857-864, August 2025.
Abstract Objective The aim of this study was to compare postoperative outcomes in patients undergoing standard laparoscopic salpingo‐oophorectomy versus those using the MiniLap percutaneous surgical system, aiming to demonstrate the non‐inferiority of this ultra‐minimally invasive surgical technique compared to the current gold standard.
Stefano Restaino, Federico Paparcura, Martina Arcieri, Alice Poli, Giulia Pellecchia, Giorgio Bogani, Cristina Taliento, Luigi Della Corte, Federica Perelli, Jvan Casarin, Salvatore Gueli Alletti, Tiziana Bove, Teresa Dogareschi, Lorenza Driul, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli   +17 more
wiley   +1 more source

Etomidato e vecurônio na indução anestésica de cardiopatas chagásicos crônicos Etomidate and vecuronium in induction of anesthesia of chronic chagasic cardiac patients

Revista da Sociedade Brasileira de Medicina Tropical, 1999
Com o objetivo de avaliar as respostas hemodinâmicas e cardiovasculares durante a indução anestésica com etomidato (hipnótico) e vecurônio (bloqueador neuromuscular) na doença de Chagas humana analisaram-se 41 pacientes (15 chagásicos e 26 não chagásicos)
Nilson de Camargos Roso, João Abrão, José Álves Neto   +2 more
doaj   +1 more source

A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]

, 2007
This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core  

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, Volume 20, Issue 7, Page 710-726, July 2025.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

DISTRIBUTION AND KINETICS OF 14C-VECURONIUM IN RATS AND MICE [PDF]

, 2017
The distribution and kinetics of 14C-vecuronium were studied in rats and mice. 14C-Vecuronium accumulated rapidly in the liver. Both unchanged and metabolized vecuronium were excreted with the bile into the intestines and stomach. Reabsorption in the gut
KAISER-SCHÖNENBERGER, E., SIN-REN, A. CHANG, WASER, P. G., WIEDERKEHR, H.   +3 more
core  

Evaluation of Integrated Arterial Filter Oxygenator vs. External Arterial Filters on Clinical Outcomes and Neurocognitive Function in Pediatric Cardiac Surgery: A Prospective Randomized Controlled Trial (RCT)

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Innovative advancements in cardiopulmonary bypass (CPB) configurations, such as surface coating, blood filtration, and miniaturization, aim to reduce gaseous microemboli (GME) that contribute to embolic organ damage, particularly neurological dysfunction.
Vishal Vinayak Bhende, Mathangi Krishnakumar, Dushyantkumar Mukundbhai Parmar, Arunkumar Ghanshyambhai Rudakiya, Tanishq Shashikant Sharma, Amit Kumar, Paresh Dilip Nerurkar, Saptak Piyush Mankad, Mamta Roshan Patel   +8 more
wiley   +1 more source

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]

, 2013
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Abdala, Ana P, Hendy, Emma B, Marvar, Paul, McBryde, Fiona D, Moraes, Davi J A, Paton, Julian F R, Pijacka, Wioletta, Sobotka, Paul A   +7 more
core   +2 more sources