Results 251 to 260 of about 5,090,064 (337)

Agent‐Based Computational Modeling of the Stochastic Dynamic Behavior of Actin Filaments Recapitulates the Homeostatic Cortical Array in Plant Epidermal Cells

open access: yesCytoskeleton, EarlyView.
ABSTRACT The homeostatic cortical actin array in plant cells plays important roles in fundamental processes, including intracellular transport, secretion, cell expansion, and cytoplasmic streaming. In response to diverse chemical and mechanical signals, the cortical array can remodel within minutes to assume new configurations or altered filament ...
June Hyung Kim   +4 more
wiley   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

open access: yesDeep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh   +12 more
wiley   +1 more source

Environmental and local habitat variables as predictors of trophic interactions in subtidal rocky reefs along the SE Pacific coast

open access: yesEcography, EarlyView.
Temperature generally drives latitudinal patterns in the strength of trophic interactions, including consumption rates. However, local community and other environmental conditions might also affect consumption, disrupting latitudinal gradients, which results in complex large‐scale patterns.
Catalina A. Musrri   +6 more
wiley   +1 more source

Developing a macroecology for human‐altered ecosystems

open access: yesEcography, EarlyView.
Although anthropogenically‐induced ecological disruptions are fundamentally important in defining ecosystem properties, they are largely overlooked by macroecological theory. Anthropogenic disruptions and their effects are generally not comparable to one another, nor to disturbances that are part of natural disturbance regimes.
Erica A. Newman   +7 more
wiley   +1 more source

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