Results 71 to 80 of about 7,284,948 (286)

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Heathland vegetation of the Spirits Bay area, far northern New Zealand [PDF]

, 1989
The heath land vegetation of northern New Zealand is usually regarded as a "derived" vegetation type resulting from forest destruction during the Maori and European periods of settlement.
Enright, N.J.
core  

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Multiple Comparison of Effect of Tree,Shrub and Grass in the Plot on Soil and Water Conversation in the Red Soil Area of Southern China

Shuitu baochi yanjiu, 2013
Assessing the effects of vegetation on soil and water conversation is the key basis for research and management of ecological restoration in water-eroded areas.In this study,the runoff depth,soil loss and corresponding precipitation of five plots planted
PENG Shao-yun1, GU Zhu-jun2, XIU Ping1
doaj  

Species Distribution and Forest Type Mapping in Mexico [PDF]

, 2009
The study analyzed the potential of multi-temporal satellite remote sensing data (Terra-MODIS) for phenological studies in Mexico. Within two conceptually and methodologically independent approaches, we analyzed vegetation index data to continuously ...
Cord, Anna, Schmidt, Michael, Dech, Stefan, Anna Cord, Colditz, Rene, Rene R. Colditz, Stefan Dech, Michael Schmidt   +7 more
core   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Vegetation context and climatic limits of the Early Pleistocene hominin dispersal in Europe [PDF]

, 2010
The vegetation and the climatic context in which the first hominins entered and dispersed in Europe during the Early Pleistocene are reconstructed, using literature review and a new climatic simulation. Both in situ fauna and in situ pollen at the twelve
Mikolajewicz, U, Arpe, K, Leroy, SAG
core   +3 more sources

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

On the Suitability of MODIS Time Series Metrics to Map Vegetation Types in Dry Savanna Ecosystems: A Case Study in the Kalahari of NE Namibia [PDF]

, 2009
The characterization and evaluation of the recent status of biodiversity in Southern Africa’s Savannas is a major prerequisite for suitable and sustainable land management and conservation purposes.
Martin Herold, Gessner, U., Hüttich, Christian, Dech, Stefan, Herold, M., Strohbach, B., Strohbach, Ben, Ursula Gessner, Hüttich, C., Stefan Dech, Ben J. Strohbach, Keil, M., Ben J. Strohbach, Dech, S., Manfred Keil, Schmidt, M., Gessner, Ursula, Herold, Martin, Keil, Manfred, Christian Hüttich, Michael Schmidt   +20 more
core   +1 more source