Results 141 to 150 of about 88,074,208 (247)
A vehicle routing model with split delivery and stop nodes [PDF]
In this work, a new variant of the Capacitated Vehicle Routing Problem (CVRP) is presented where the vehicles cannot perform any route leg longer than a given length L (although the routes can be longer).
Leonardo Berbotto +2 more
core
Advanced Science, EarlyView.ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo +10 more
wiley +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
The Vehicle Rescheduling Problem [PDF]
The capacitated vehicle routing problem is to find a routing schedule describing the order in which geographically dispersed customers are visited to satisfy demand by supplying goods stored at the depot, such that the traveling costs are minimized.
Dekker, R., Spliet, R., Gabor, A.F.
core
Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy
Advanced Science, EarlyView.A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan +9 more
wiley +1 more source
Shuffle frequency migration of 4WD vehicle [PDF]
This paper explains the method to examine the driveability of Four Wheels Drive vehicle. One of key elements to assess the vehicle driveability is to expose the vehicle under harsh driving conditions such as feeding the crankshaft with wide open ...
Bin Raja Ahsan Shah, Raja Mazuir +3 more
core
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
A Security-Enhanced Certificateless Aggregate Signature-Based Conditional Privacy-Preserving Authentication Scheme for VANETs. [PDF]
Sensors (Basel)Wang R, Liu C, Zhang H, Jia M.
europepmc +1 more source
Advanced Science, EarlyView.A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang +7 more
wiley +1 more source
Rate Book of Weights and Fees, 1922-1931 [Incomplete]
Issued 1921-1929 by the Secretary of State's Vehicle Registration Department and 1930-1931 by the Kansas Vehicle Department.Rate Book of Weights and Fees, State of Kansas, 1922 Rate Book of Weights and Fees, State of Kansas, Second Edition (Revised ...
Kansas. Vehicle Department
core +1 more source