Results 91 to 100 of about 32,663,247 (352)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Enhancing motorway traffic data with novel vehicle re-identification algorithms
, 2006 This paper describes recent work in vehicle re-identification procedures applied to individual vehicle data (IVD) from highway inductance loop ...
Wilson, RE, Lunt, George, Day, MA
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Health initiatives to target obesity in surface transport industries: review and implications for action [PDF]
, 2015 Lifestyle-related chronic diseases pose a considerable burden to the individual and the wider society, with correspondingly negative effects on industry.
J Chapman (9858083) +5 more
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ASSESSMENT OF VEHICLE EFFECTIVE MODERNIZATION TAKING INTO ACCOUNT THE LIFE CYCLE COST, TECHNICAL AND ENVIRONMENTAL PARAMETERS [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2016 The article deals with the features for determination of the efficiency of vehicle modernization compared to the base one. They propose the model for determining the efficiency of vehicle mod-ernization compared with the base one.
M. Volodarets
doaj
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The Pyramidal Capacitated Vehicle Routing Problem [PDF]
This paper introduces the Pyramidal Capacitated Vehicle Routing Problem (PCVRP) as a restricted version of the Capacitated Vehicle Routing Problem (CVRP).
Lysgaard, Jens
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Topology optimization of a ratchet compensation structure subject to periodic constraints
High-Speed RailwayThe railway pantograph-catenary system employs a ratchet compensation device to sustain the tension of the contact wire. However, the excessive weight associated with the ratchet structure adversely affects the performance of the compensation device.
Taining Qi +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Improved Information Processing for Cooperative Vehicle Safety Applications
, 2006 Current Vehicle-to-Vehicle and Vehicle-to-Roadside communication based on IEEE 802.11 cannot guarantee a reliable dissemination of situational information which is required for Situation-Aware Driver Assistance Systems.
Strang, Thomas +3 more
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