Results 141 to 150 of about 32,663,247 (352)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Tyre / soil interaction modelling within a virtual proving ground environment [PDF]

, 2012
Off-road mobility defines the ability of land-based vehicles to accelerate, pull loads and climb gradients. Historically, much of the work completed to relate mobility to vehicle and terrain characteristics has been empirical in nature, and has ...
Wright, A.
core  

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries

Advanced Functional Materials, EarlyView.
A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy, Mohammad Zaid, Sayan Das, Sooryadas Sudhakaran, Shampa Aich, Vilas G. Pol   +5 more
wiley   +1 more source

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

Advanced Functional Materials, EarlyView.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat, Alexander Peraire‐Bueno, A. John Hart, Randall M. Erb   +3 more
wiley   +1 more source

Estudo para Utilização de Componentes de Suspensão de Motocicleta em Veículo Minimalista Urbano [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Engenharias da Mobilidade. Campus Joinville. Engenharia Automotiva.A utilização de componentes de suspensão de motocicleta de baixo custo e grande volume de vendas mostra-se uma ...
Demboski, Fernando Rodrigues
core  

Vehicle temperature identification based on vehicle dimensions during vehicle parking

BIS Energy and Engineering
Increased car temperature when parked in sunlight results in discomfort for the driver and passengers, and can damage the inside the car, including the dashboard, seats, and control panel. Research This study was conducted to measure the increase in vehicle cabin temperature when parked in the sun from 08.20 - 16.20 WIB.
Syifa Mar’atus Saleha, Mutiara Vinta Andani, Gustia Ramadhani, Wawan Purwanto, Hendra Dani Saputra, M. Yasep Setiawan   +5 more
openaire   +1 more source

Anion‐Exchange‐Enabled Hydrogel Electrolytes With High Zn2+ Transference for Dendrite‐Free Flexible Zinc‐Ion Batteries

Advanced Functional Materials, EarlyView.
A high‐Zn2+‐transference hydrogel electrolyte of ex‐PDADAM is developed via anion exchange at quaternary ammonium sites, achieving high Zn2+ transference number (0.86), ionic conductivity (8.10 mS cm−1), and toughness (51.25 MJ m−3). Symmetric cells are operated stably for over 2000 h, while flexible pouch cells retain 90.9% capacity after 300 cycles ...
Jung Woo Hong, Yeon Su Kim, Zuyang Hu, Hyungyu Cho, Gun Jang, Minjun Hwang, Hye Rin Park, Jun Su Kim, Ho Seok Park   +8 more
wiley   +1 more source

Artificial Intelligence-Based Electric Vehicle Smart Charging System in Malaysia

World Electric Vehicle Journal
The worldwide transition to electric vehicles (EVs) is gaining momentum, propelled by the imperative to reduce carbon emissions and foster sustainable transportation.
Siow Jat Shern, Md. Tanjil Sarker, Gobbi Ramasamy, Siva Priya Thiagarajah, Fahmid Al Farid, S. Suganthi   +5 more
semanticscholar   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source