Results 161 to 170 of about 29,524 (312)

A FAP‐Targeted SMDC Platform Enables Synergistic Radionuclide–Chemotherapy with PET‐Guided Evaluation

Advanced Science, EarlyView.
A fibroblast activation protein (FAP)‐targeted small molecule–drug conjugate (SMDC) platform is developed to integrate PET imaging with synergistic radionuclide–chemotherapy. Linker chemistry governs stability, exposure, and tolerability, with the VC linker providing superior in vivo performance.
Ruitao Yang, Hongxin Li, Zexin Xu, Baocheng Chen, Ningjie Li, Yuhua Zhong, Kongzhen Hu   +6 more
wiley   +1 more source

Mapping the intellectual structure of the refrigerated vehicle routing problem: research perspectives and structural knowledge gaps. [PDF]

Front Res Metr Anal
Aristizábal Torres D, Peñuela Meneses CA, Santa Chávez JJ, Escobar Falcón LM.   +3 more
europepmc   +1 more source

An innovative medical waste management system in a smart city using XAI and vehicle routing optimization. [PDF]

F1000Res, 2023
Boudanga Z, Benhadou S, Medromi H.
europepmc   +1 more source

Programmable Hydration Pathways Enable Reconfigurable Ionic Thermoelectrics for Energy Harvesting and Thermal‐Tactile Interaction

Advanced Science, EarlyView.
Programmable hydration pathways enable reconfigurable ionic thermoelectrics in polyquaternium hydrogels. By coupling microscopic solvation, mesoscale water channels, and macroscopic boundary control, hydration‐gated protonics decouples thermopower, response speed, and stability.
Zehao Zhao, Yun Shen, Dongyan Xu
wiley   +1 more source

Research on joint vehicle routing optimization considering multiple distribution centers. [PDF]

PLoS One
Liu D, Li M, Lei Y, Yu P, Li B, Tang S.
europepmc   +1 more source

Bipolar Covalent Organic Frameworks Crafting Core–Shell Heterostructured Cathode for High–Performance Lithium–Organic Batteries

Advanced Science, EarlyView.
A bipolar CNT@COF core–shell heterostructure cathode constructed via synergistic molecular and microstructural engineering enables rapid electron/ion transport and efficient utilization of electroactive groups for high–performance lithium–organic batteries. ABSTRACT Covalent organic frameworks (COFs) with tunable molecular structures and ordered porous
Yalong Jiang, Nan Jiang, Yu Dou, Zixuan Chen, Yunhai Zhu, Long Chen, Yingkui Yang   +6 more
wiley   +1 more source

Data describing planned routes and driven routes from a last-mile delivery vehicle routing problem. [PDF]

Data Brief
Konovalenko A, Hvattum LM, Iversen KAH.
europepmc   +1 more source

Benchmarking a fast, satisficing vehicle routing algorithm for public health emergency planning and response: "Good Enough for Jazz". [PDF]

PeerJ Comput Sci, 2023
McDaniel EL, Akwafuo S, Urbanovsky J, Mikler AR.   +3 more
europepmc   +1 more source

Two-phase heuristic for capacitated vehicle routing problem

, 2010
Vehicle Routing Problem (VRP) is a NP-complete problem and has important practical value. The Capacitated Vehicle Routing Problem (CVRP) constrained by the capacity of a vehicle is the extension of VRP.
Zou WP(邹文平), Jin L(金莉), Zhu YL(朱云龙), Shen H(申海)   +3 more
core  

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source