Enhanced vehicle routing for medical waste management via hybrid deep reinforcement learning and optimization algorithms. [PDF]
Front Artif IntellKhallaf N +4 more
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Advanced Science, EarlyView.Impurity tolerance in LiFePO4 cathodes varies strongly with impurity type and content. Low Ni levels are accommodated within the lattice with minimal structural disruption, whereas higher Ni contents introduce antisite disorder. In contrast, Cr impurities segregate from the LiFePO4 framework, blocking lithium‐ion pathways and leading to inferior ...
Minjin Kim +3 more
wiley +1 more source
Q-Learning-Driven Butterfly Optimization Algorithm for Green Vehicle Routing Problem Considering Customer Preference. [PDF]
Biomimetics (Basel)Meng W, He Y, Zhou Y.
europepmc +1 more source
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Mixed fleet-based two-echelon vehicle routing optimization for cold chain logistics with diverse recharging strategies. [PDF]
PLoS OneLi Y, Liao W, Huang Y.
europepmc +1 more source
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
A Reactive Tabu Search Meta-Heuristic for the Vehicle Routing Problem with Divisible Deliveries and Pickups [PDF]
, 2013 Nagy, Gábor, Wassan, Niaz A.
core
Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects
Advanced Science, EarlyView.Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu +6 more
wiley +1 more source
Optimization of carbon emission in an integrated machine-piece scheduling and vehicle routing problem and its solution using MOPSO and NSGAII metaheuristic algorithms. [PDF]
Sci RepHeidari A +3 more
europepmc +1 more source