Results 91 to 100 of about 7,571 (303)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Persistent Localized Broadcasting in VANETs [PDF]

, 2013
We present a communication protocol, called LINGER, for persistent dissemination of delay-tolerant information to vehicular users, within a geographical area of interest.
Borsetti, Diego Ferruccio, CHIASSERINI, Carla Fabiana, Casetti, Claudio, Casetti, Claudio Ettore, Fiore, Marco, Chiasserini, Carla-Fabiana, Borsetti, Diego, Chiasserini C.-F.   +7 more
core   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

IEEE Access Special Section Editorial: Resource Management in Vehicular Adhoc Networks: Energy Management, Communication Protocol and Future Applications

IEEE Access, 2017
The advancements in technology have transformed the vehicles moving around us into intelligent machines. These vehicles now have the capabilities to communicate and share useful information with each other under a communication network known as Vehicular
Tariq Umer, Mubashir Husain Rehmani, Zhi Guo Ding, Byung-Seo Kim, Samee U. Khan   +4 more
doaj   +1 more source

A Lightweight CP-ABE Scheme with Direct Attribute Revocation for Vehicular Ad Hoc Network. [PDF]

Entropy (Basel), 2023
Liu Y, Xu S, Yue Z.
europepmc   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Hierarchical wireless framework for real-time collaborative generation and distribution of telemetry data

, 2010
This project introduces a novel multidisciplinary approach combining Vehicular Ad Hoc Networks and Granular Computing, to the data processing and information generation problem in large urban traffic systems.
Kucukdurgut, I
core  

Vehicular ad hoc Networks [PDF]

, 2015
MISIC, JELENA, Molinaro, Antonella, Campolo, Claudia, ÖZTÜRK, Serkan, MISIC, VOJISLAV B., Scopigno, Riccardo   +5 more
  +6 more sources

A Novel Energy-Efficient Reservation System for Edge Computing in 6G Vehicular Ad Hoc Network. [PDF]

Sensors (Basel), 2023
Javed F, Khan ZA, Rizwan S, Shahzadi S, Chaudhry NR, Iqbal M.   +5 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source