Results 231 to 240 of about 155,535 (377)

Translating, resisting, or escalating government programs? Accounting at the intersection of centrally imposed programs and local responses

open access: yesContemporary Accounting Research, EarlyView.
Abstract This article examines the role of accounting in the recursive processes of continuous adjustment to programs that emerge when programs are imposed by central government on local government. Focusing on the Italian context and adopting the conceptual lens of governmentality, our study contributes to the extant literature by highlighting the ...
Ileana Steccolini, Carmela Barbera
wiley   +1 more source

An improved deep reinforcement learning routing technique for collision-free VANET. [PDF]

open access: yesSci Rep, 2023
Upadhyay P   +7 more
europepmc   +1 more source

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

open access: yesAging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik   +20 more
wiley   +1 more source

At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle

open access: yesAging Cell, EarlyView.
Injury then recovery markedly rewires the DNA methylome in aged skeletal muscle.The addition of senolytics during muscle regeneration decelerates DNAmAGE more than regeneration alone as well as targets collagen remodeling and stem cell function‐related genes.
Toby L. Chambers   +16 more
wiley   +1 more source

Efficient traffic management with adaptive SDN in vehicular networks. [PDF]

open access: yesSci Rep
Rajan SJ   +8 more
europepmc   +1 more source

Combined Effects of Mechanical Loading and Piezo1 Chemical Activation on 22‐Months‐Old Female Mouse Bone Adaptation

open access: yesAging Cell, EarlyView.
In vivo mechanical loading combined with Yoda2 injection produced an additive effect on cortical bone parameters in the tibiae of 22‐month‐old female mice. In vivo calcium signaling results suggest that Yoda2 could reach osteocytes and activate Piezo1.
Quentin A. Meslier   +2 more
wiley   +1 more source

Accumulation of GSK‐3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission

open access: yesAging Cell, EarlyView.
Overexpression of GSK‐3β in DG GABAergic neurons impairs neurogenesis by reducing GABA release, which can be reversed by enhancing GABAergic transmission. ABSTRACT The activation of glycogen synthase kinase 3β (GSK‐3β) and the deterioration of spatial memory represent prominent pathological and clinical manifestations of Alzheimer's disease (AD ...
Fei Liu   +11 more
wiley   +1 more source

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