Results 271 to 280 of about 47,897 (311)

An SGLT2 inhibitor, canagliflozin, reduces blood glucose level in the renal capillaries and protects the capillary network in the diabetic rats

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Sodium‐glucose cotransporter 2 (SGLT2) inhibitors consistently demonstrate renal protection against progressive kidney disease. We hypothesised that SGLT2 inhibition reduces blood glucose levels in peri‐proximal tubular capillaries by limiting reabsorption from the tubular filtrate, thereby safeguarding the renal microvasculature from ...
Anqi Zhang   +5 more
wiley   +1 more source

Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims In the therapy of type 1 diabetes mellitus, the subcutaneous space has been suggested to be a clinically preferable transplantation site for pancreatic islets due to its easy accessibility. However, its poor vascularisation capacity and, thus, challenging environment typically result in islet engraftment failure.
Selina Wrublewsky   +11 more
wiley   +1 more source

Mesenchymal Stem Cell Therapy for Perianal Crohn's Disease: Surgical Appraisal of Evidence and Translational Potential

open access: yes
ANZ Journal of Surgery, EarlyView.
Rathin Gosavi   +7 more
wiley   +1 more source

Tryptophan derivatives as non‐invasive diagnostic indicators for obesity‐related MASLD in children and adolescents

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents a major health burden in children and adolescents with obesity. This study aimed to characterize metabolic alterations associated with obesity‐related MASLD and to evaluate the potential of tryptophan (TRP)‐derived metabolites as non‐invasive biomarkers for early ...
Shumin Zhan   +20 more
wiley   +1 more source

Sectoral Adaptation and Strategic Resilience: The Impact of Sanctions on Russian Corporate Performance (2014–2021)

open access: yesEconomics of Transition and Institutional Change, EarlyView.
ABSTRACT We examine the sectoral impact of Western sanctions on Russian corporate performance from 2014 to 2021 using a panel of listed nonfinancial firms. Applying continuous‐time heterogeneous treatment models and difference‐in‐differences estimators, we document persistent divergence across sectors: The energy sector exhibits sustained ...
Eugene Nivorozhkin
wiley   +1 more source

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