Results 281 to 290 of about 47,897 (311)

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen   +25 more
wiley   +1 more source

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to assess the therapeutic efficacy of galcanezumab in preclinical models of migraine and cluster headache and to determine potential shared trigeminovascular mechanisms of action. Galcanezumab is a humanized monoclonal antibody that binds to the neuropeptide calcitonin gene‐related peptide ...
Marta Vila‐Pueyo   +3 more
wiley   +1 more source

DAF-Aided ISAC Spatial Scattering Modulation for Multi-Hop V2V Networks. [PDF]

open access: yesSensors (Basel)
Fan Y   +8 more
europepmc   +1 more source

Circular economy business strategies and public schemes: a game theory‐based survey

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract This paper develops a selected survey based on game theory in circular economy (CE) by complementing two perspectives: the CE business strategies and the public schemes (PS) available to implement CE systems. These perspectives are concentrated in six CE business strategies (circular inputs, sharing platforms, product‐as‐a‐service (PaaS ...
Vinay Ramani, Pietro De Giovanni
wiley   +1 more source

Reinforcement learning based route optimization model to enhance energy efficiency in internet of vehicles. [PDF]

open access: yesSci Rep
Hussain Q   +7 more
europepmc   +1 more source

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