Results 51 to 60 of about 7,571 (303)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Networking algorithm based on self-organizing map neural network for VANET
Tongxin xuebao, 2011 An approach was proposed to apply a self-organizing map neural network to organize vehicular ad hoc net-works,which were used for car driving-aid systems and automatic driverless systems in intelligent transportation area.Based on the location and ...
WU Yi1 +4 more
doaj +2 more sources
On-demand Misbehavior Detection for Vehicular Ad Hoc Network
International Journal of Distributed Sensor Networks, 2016 Maintaining communication links of an established communication path that extends between source and destination nodes is a significant challenge in Vehicular Ad Hoc Networks due to movement of the vehicles. Operations of Vehicular Ad Hoc Network rely on
Yao-Hua Ho, Chun-Han Lin, Ling-Jyh Chen
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The Security Perspectives of Vehicular Networks: A Taxonomical Analysis of Attacks and Solutions
Applied Sciences, 2021 Vehicular networks are the combination of transport systems and the internet systems formed with the main motive to increase the safety of passengers, although non-safety applications are also provided by vehicular networks.
Amandeep Verma +3 more
doaj +1 more source
Improving VANETs Connectivity with a Totally Ad Hoc Living Mobile Backbone
Journal of Computer Networks and Communications, 2015 The vehicular ad hoc network (VANET) for intelligent transportation systems is an emerging concept to improve transportation security, reliability, and management.
Joilson Alves Junior, Emilio C. G. Wille
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
A robust self-organized public key management for mobile ad hoc networks
, 2010 A mobile ad hoc network (MANET) is a self-organized wireless network where mobile nodes can communicate with each other without the use of any existing network infrastructure or centralized administration. Trust establishment and management are essential
Dahshan, Hisham M.K., Irvine, J.
core +1 more source
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
A Novel Blockchain Based Secured and QoS Aware IoT Vehicular Network in Edge Cloud Computing
IEEE Access, 2022 A software-defined vehicular network is made up of an IoT (Internet of Things) based vehicular ad-hoc network and a software-defined network. For better communication in IoT based vehicle networks, researchers are now working on the VANET (Vehicular Ad ...
Adeel Ahmed +5 more
doaj +1 more source