Results 251 to 260 of about 9,870 (306)

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman   +5 more
wiley   +1 more source

Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Hyperactivity is a persistent and clinically relevant symptom in anorexia nervosa (AN). Hyperactivity is inversely correlated with leptin levels. While systemic leptin administration attenuates hyperactivity in rodent models, the specific brain regions mediating this effect remain unclear.
Nick J. M. Papavoine   +6 more
wiley   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock   +2 more
wiley   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

open access: yesExploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng   +11 more
wiley   +1 more source

Privacy protection on Vehicular Ad hoc NETworks

open access: yesInternational Journal of Ad Hoc and Ubiquitous Computing, 2011
Vehicular Ad hoc NETwork (VANET) provides traffic safety and efficient traffic management by taking advantage of messages that are quickly interchanged among vehicles and some infrastructures. The integrity and non-repudiation of messages and vehicle privacy in VANET are quite critical. Pseudonym technology is a practical strategy to ensure these three
Ren-Junn Hwang   +2 more
openaire   +2 more sources

Ads dissemination in Vehicular Ad Hoc Networks

2015 IEEE International Conference on Communications (ICC), 2015
Advertisements(Ads) dissemination in Vehicular Ad Hoc Networks (VANETs) is a promising application. It not only provides benefits to customers but also brings commercial profits to merchants. However, little previous work has focused on the ads dissemination problem to maximize the overall profit.
Chao Wang 0061   +3 more
openaire   +1 more source

Security in vehicular ad hoc networks

IEEE Communications Magazine, 2008
Vehicular communication networking is a promising approach to facilitating road safety, traffic management, and infotainment dissemination for drivers and passengers. One of the ultimate goals in the design of such networking is to resist various malicious abuses and security attacks. In this article we first review the current standardization process,
Xiaodong Lin 0001   +5 more
openaire   +1 more source

Synchronous Relaying in Vehicular Ad-Hoc Networks

International Journal of Wireless Networks and Broadband Technologies, 2011
In this paper, the authors propose a simple concept for emergency information dissemination in vehicular ad-hoc networks. Instead of competing for the shared wireless medium when transmitting the emergency information, the authors’ proposed method requires nodes to cooperate by synchronizing their transmissions.
Dmitri Moltchanov   +3 more
openaire   +1 more source

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