Results 31 to 40 of about 2,436 (255)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
ESCOVE: Energy-SLA-Aware Edge–Cloud Computation Offloading in Vehicular Networks
Sensors, 2021 The vehicular network is an emerging technology in the Intelligent Smart Transportation era. The network provides mechanisms for running different applications, such as accident prevention, publishing and consuming services, and traffic flow management ...
Leila Ismail, Huned Materwala
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
IEEE Access, 2019 The latest research of network and computing contributes greatly to the development of vehicular networks. However, in existing works, these two important enabling technologies are studied separately.
Yaping Cui, Yingjie Liang, Ruyan Wang
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
World Electric Vehicle JournalThe convergence of vehicular communications, 5th generation mobile network (5G) technology, and edge computing marks a paradigm shift in intelligent transportation.
Salah Eddine Merzougui +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Handover-Enabled Dynamic Computation Offloading for Vehicular Edge Computing Networks
IEEE Transactions on Vehicular Technology, 2023 The computation offloading technique is a promising solution that empowers computationally limited resource devices to run delay-constrained applications efficiently. Vehicular edge computing incorporates the processing capabilities into the vehicles, and thus, provides computing services for other vehicles through computation offloading.
Homa Maleki +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
IEEE Access, 2020 The promise of low latency connectivity and efficient bandwidth utilization has driven the recent shift from vehicular cloud computing (VCC) towards vehicular edge computing (VEC).
Mashael Khayyat +5 more
doaj +1 more source