Results 71 to 80 of about 143,933 (274)

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Can cloudlet coordination support cloud computing infrastructure?

Journal of Cloud Computing: Advances, Systems and Applications, 2018
The popularity of mobile applications on smartphones requires mobile devices to perform high-performing processing tasks. The computational resources of these devices are limited due to memory, battery life, heat, and weight dissipation.
Abdullah Alsaleh
doaj   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

Fog-Based Two-Phase Event Monitoring and Data Gathering in Vehicular Sensor Networks

Sensors, 2017
Vehicular nodes are equipped with more and more sensing units, and a large amount of sensing data is generated. Recently, more and more research considers cooperative urban sensing as the heart of intelligent and green city traffic management.
Yongxuan Lai, Fan Yang, Jinsong Su, Qifeng Zhou, Tian Wang, Lu Zhang, Yifan Xu   +6 more
doaj   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

Advanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang, Xing Yang, Liping Liu, Yang Peng, Yangyang Wang, Hualiang Lv   +5 more
wiley   +1 more source

Towards Multi-Access Edge based Vehicular Fog Computing Architecture

, 2018
International audienceIn this paper, we propose a multi-access edge based vehicular fog architecture. It is based on the integration of fog computing (FC) and multi-access edge computing (MEC) with the vehicular cloud. The aim of this architecture is the
Issam Jabri, Benjemaa, Maher, Mekki, Tesnim, Jabri, Issam, Rachedi, Abderrezak, Tesnim Mekki, Maher Ben Jemaa, Abderrezak Rachedi   +7 more
core   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source

OCVC: An Overlapping-Enabled Cooperative Computing Protocol in Vehicular Fog Computing

, 2022
Vehicular fog computing (VFC) has emerged as a promising solution to relieve the overload in vehicular network. Since individual vehicular fog node is incapable of providing ultra-reliable and low-latency services constrained by limited resources ...
Wei, Zhiwei, Zhang, Rongqing, Yang, Liuqing, Cheng, Xiang, Li, Bing   +4 more
core   +1 more source

Oblivious Transfer-Based Authentication and Privacy-Preserving Protocol for 5G-Enabled Vehicular Fog Computing

IEEE Access
The fast development of vehicle technology and the appearance of 5G networks have brought new opportunities as well as challenges for vehicular fog computing.
Zeyad Ghaleb Al-Mekhlafi, Saima Anwar Lashari, Jalal Mohammed Hachim Altmemi, Mahmood A. Al-Shareeda, Badiea Abdulkarem Mohammed, Amer A. Sallam, Bassam Ali Al-Qatab, Mohammad T. Alshammari, Abdulaziz M. Alayba   +8 more
doaj   +1 more source

Experimental Demonstration of Temporally Aware Fault‐Tolerant Sensor Fusion Using Memristive Associative Learning

Advanced Electronic Materials, EarlyView.
In dynamic driving scenarios, the proposed approach ensures only temporally aligned sensor inputs to make driving decisions, preventing false activations. By enabling selective hardware‐level learning, it achieves fast, reliable responses under noisy conditions.
Kapil Bhardwaj, Ashfak Nehal, Dmitrii Semenov, Roman Sotner, Sayani Majumdar   +4 more
wiley   +1 more source