Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
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Bistability coordinates activation of the EGFR and DPP pathways in Drosophila vein differentiation
Molecular Systems Biology, 2009 Cell differentiation in developing tissues is controlled by a small set of signaling pathways, which must coordinate the timing and levels of activation to ensure robust and precise outcomes. Highly coordinated activation of signaling pathways can result
Shian‐Jang Yan +5 more
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Advanced Functional Materials, EarlyView.This study introduces a paper‐based biodegradable, humidity‐insensitive e‐nose for real‐time breath analysis, addressing challenges in existing technologies such as humidity interference, high costs, and environmental impact. Featuring hydrophobic polymer coatings, these sensors reliably detect VOCs even in high‐moisture environments.
Indrajit Mondal +2 more
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Frontiers in Pharmacology, 2014 The endothelium is a multifunctional heterogeneous tissue playing a key role in the physiology of every organ. To accomplish this role the endothelium presents a phenotypic diversity that is early prompted during vascular development, allowing it to cope
Paola eCasanello +5 more
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Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
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Dual Function for Mature Vascular Smooth Muscle Cells During Arteriovenous Fistula Remodeling
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundThe arteriovenous fistula (AVF) is the preferred form of hemodialysis access for patients with chronic kidney disease. However, AVFs are associated with significant problems including high incidence of both early and late failures, usually ...
Jinjing Zhao +9 more
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TWO CASES OF VEIN-GRAFTING FOR THE MAINTENANCE OF A DIRECT ARTERIAL CIRCULATION. [PDF]
, 1913 J Hogarth Pringle
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Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
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Jornal Vascular Brasileiro, 2011 Os aneurismas venosos são raros, porém causam complicações tromboembólicas. Na maioria das vezes, são encontrados como achados de exame físico ou de imagem.
Bruno Morisson +5 more
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The Wing Veins of Insects . By Professor C. W. Woodworth. University of California Publications, Technical Bulletins, College of Agriculture, Agricultural Experiment Station. Entomology, Vol. I., No. 1, pp. 1-152, September, 1906. Contributions from the Zoological Laboratory of the Museum of Comparative Zoology at Harvard College, under the direction of B. L. Mark. No. 181. [PDF]
, 1907 James G. Needham
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