Results 21 to 30 of about 835,120 (286)

Investigation on the Lift Force Induced by the Interceptor and Its Affecting Factors: Experimental Study with Captive Model

Journal of Marine Science and Engineering, 2022
An interceptor is an appendage widely used for high-speed planing boats to reduce resistance and modify hull attitude by the lift force-induced, but the relationship between the induced lift force and the factors affecting it are still not clear ...
Rui Deng, Zezhen Zhang, Fuqiang Luo, Pengnan Sun, Tiecheng Wu   +4 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD

Respiratory Research
Background Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition. Given patients with COPD continue to experience exacerbations despite the availability of effective therapies, anti-inflammatory treatments targeting novel ...
Mirco Govoni, Michele Bassi, Luca Girardello, Germano Lucci, François Rony, Rémi Charretier, Dmitry Galkin, Maria Laura Faietti, Barbara Pioselli, Gloria Modafferi, Rui Benfeitas, Martina Bonatti, Daniela Miglietta, Jonathan Clark, Frauke Pedersen, Anne-Marie Kirsten, Kai-Michael Beeh, Oliver Kornmann, Stephanie Korn, Andrea Ludwig-Sengpiel, Henrik Watz   +20 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of inhaled beclometasone dipropionate/formoterol fumarate/glycopyrronium vs. beclometasone dipropionate/formoterol fumarate and placebo on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease: a randomised controlled trial

Respiratory Research
Background The single-inhaler triple combination of beclometasone dipropionate, formoterol fumarate, and glycopyrronium (BDP/FF/G) is available for maintenance therapy of chronic obstructive pulmonary disease (COPD).
Henrik Watz, Anne-Marie Kirsten, Andrea Ludwig-Sengpiel, Matthias Krüll, Robert M. Mroz, George Georges, Guido Varoli, Rémi Charretier, Mauro Cortellini, Andrea Vele, Dmitry Galkin   +10 more
doaj   +1 more source

Safety and immunogenicity of an mRNA-based RSV vaccine in seropositive children aged 12–59 months

Human Vaccines & Immunotherapeutics
Respiratory syncytial virus (RSV) is a common respiratory pathogen in children. After demonstrating safety and immunogenicity in adults, mRNA-1345 encoding the RSV prefusion (preF) stabilized F glycoprotein was investigated in children.
Sabine Schnyder Ghamloush, Sue Fanning, Brandon Essink, Frank Eder, Matthew D. Snape, Sonia K. Stoszek, Ruiting Guo, Rakesh Dhar, Vinicius Righi, Louie Morsy, Archana Kapoor, Laila El Asmar, Christine A. Shaw   +12 more
doaj   +1 more source

A Correlational Analysis of Shuttlecock Speed Kinematic Determinants in the Badminton Jump Smash

Applied Sciences, 2020
The forehand jump smash is an essential attacking stroke within a badminton player’s repertoire. A key determinate of the stroke’s effectiveness is post-impact shuttlecock speed, and therefore awareness of critical technique factors that ...
Mark King, Harley Towler, Romanda Dillon, Stuart McErlain-Naylor   +3 more
doaj   +1 more source

Analysis of the future trends of typical mountain glacier movements along the Sichuan-Tibet Railway based on ConvGRU network

International Journal of Digital Earth, 2023
The anomalous movements of glaciers cause disasters, such as debris flows and landslides. It is very important to assess the glacier movements and their future trends. Glacier velocity refers to movement process. The current research aims to analyse past
Yali Zhang, Lifeng Zhang, Yi He, Sheng Yao, Wang Yang, Shengpeng Cao, Qiang Sun   +6 more
doaj   +1 more source

Average error determination in the calculation of earthquake epicenter coordinates

Вестник Дагестанского государственного технического университета: Технические науки, 2021
Objective. The study is aimed at determining the dependence of the average error in calculating the epicenter coordinates of an earthquake on errors in measuring the velocities of seismic waves for various methods of seismic event localization.
G. K. Aslanov, T. G. Aslanov
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source