Results 171 to 180 of about 2,660,132 (330)

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Determining force-velocity isokinetic capacities to individualize muscle strengthening in sports rehabilitation. [PDF]

Int J Sports Phys Ther
Moiroux-Sahraoui A, Forelli F, Samozino P.   +2 more
europepmc   +1 more source

Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development

Advanced Science, EarlyView.
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan, Di Wu, Mei‐Zhi Wang, Zhong‐Yi Chen, Jian‐Feng Lv, Yu‐Hui Xia, Zhe‐Nan Wang, Wen Luo, Xin‐Lu Xu, Xue‐Qing Yan   +9 more
wiley   +1 more source

Sensor-Based Assessment of Asymmetry in Upper Limb Bradykinesia Among Patients With Parkinson's Disease and Scans Without Evidence of Dopaminergic Deficit (SWEDD). [PDF]

Parkinsons Dis
Kwon DY, Ko J, Kwon Y, Kim JW.
europepmc   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

Advanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu, Nhu An Phan, Sy Trung Ngo, Minh Tri Phan, Thanh‐An Truong, Chi Cong Nguyen, Phuoc Thien Phan, Hoang‐Phuong Phan, Thanh Nho Do, Mai Thanh Thai   +9 more
wiley   +1 more source

Homonymous hemianopia in posterior cortical atrophy: right-left asymmetry, progression over time and relationship to the classical neuropsychological deficits. [PDF]

Front Neurol
Maia da Silva MN, James-Galton M, Green C, Plant GT.   +3 more
europepmc   +1 more source

Rapid Room‐Temperature Synthesis of Te4+‐Doped Cs2ZrCl6 Vacancy‐Ordered Double Perovskites With Tunable Luminescence Triggered by Extreme Conditions for Advanced Optical Thermometry and Manometry

Advanced Science, EarlyView.
Through utilizing a proposed rapid room‐temperature precipitation method, the Te4+‐doped Cs2ZrCl6 vacancy‐ordered doubles with intense STE emission were synthesized. Via using the extreme conditions, i.e., temperature and pressure, stimulus, the luminescence properties of the resulting compounds are significantly modulated, endowing their promising ...
Zhiyu Pei, Yeshan Wu, Shuailing Ma, Tian Cui, Laihui Luo, Peng Du   +5 more
wiley   +1 more source

Bench-Press Performed With a Velocity- and Tempo-Based Approach: Are There Differences in Volume Load, Time Under Tension, and Metabolic Demands? [PDF]

Sports Health
Fitas A, Miras-Moreno S, Oliveira JH, Cidrais M, Pezarat-Correia P, Schoenfeld BJ, Mendonca GV.   +6 more
europepmc   +1 more source

Molecularly Engineered Phenoxazinone‐Skeleton Cascade‐Activated NIR Probes for Monitoring Fe2+/Viscosity in Ferroptosis‐Mediated Parkinson's Disease

Advanced Science, EarlyView.
A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo, Tao Liu, Hongfei Wang, Qi Gao, Zhaobo Yang, Zumeng Wang, Chenlong Li, Yubing Kang, Kahleong Lim, Wen Liu, Li Lu, Chengwu Zhang   +11 more
wiley   +1 more source

Effectiveness of Individualized Training Programs Based on the Optimal Force-Velocity Relationship to Develop Athletes' Jump Performance: A Systematic Review with Meta-Analysis. [PDF]

J Hum Kinet
Li Z, Zhi P, Zhang X, Bai J, García-Ramos A, Janicijevic D.   +5 more
europepmc   +1 more source