Results 61 to 70 of about 54,131 (295)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Numerical Simulation of Pollutant Channeling between Adjacent Road Tunnels [PDF]

E3S Web of Conferences
With the development of highway tunnels, the increasing number of continuous tunnels has brought forth a growing concern regarding the dispersion of pollutants between tunnel entrances.
Tang Sha, Han Xiaoyang, Zhi Yansheng
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Velocity dispersion of correlated energy spread electron beams in the free electron laser

New Journal of Physics, 2017
The effects of a correlated linear energy/velocity chirp in the electron beam in the free electron laser (FEL), and how to compensate for its effects by using an appropriate taper (or reverse-taper) of the undulator magnetic field, is well known.
L T Campbell, A R Maier
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

The Velocity Dispersion Profile of Nine Open Clusters in the Solar Neighborhood

The Astrophysical Journal
We analyze the velocity dispersion profiles of nine open clusters in the solar neighborhood using kinematic data from Gaia DR 3, aiming to identify potential dynamical signatures of stellar-mass black holes through a comparison of theoretical and ...
Bingqian Ma, Xiaoying Pang, Sambaran Banerjee, Pengfei Ren, M. B. N. Kouwenhoven   +4 more
doaj   +1 more source

On the ability of the Generalized Continuum Transport Model to properly capture dispersion

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2018
The ability of the Generalized Continuum Transport model to describe dispersion is studied through the comparison of the breakthrough curves with an analytical solution of the linear advection-dispersion Equation.
Vasilyev Leonid, Radu Florin Adrian
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

On Radial Heat Transport in Porous Aquifers With Nonlinear Velocity‐Dependent Thermal Dispersion

Water Resources Research
Accurate modeling of heat transport behavior near the test well is essential for the efficient operation and management of aquifer thermal energy storage (ATES) systems.
Wenguang Shi, Quanrong Wang, Ying‐Fan Lin, Aohan Jin, Yingfan Zhao, Yanxin Wang, Chong Ma   +6 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source