This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
STELLAR VELOCITY DISPERSION MEASUREMENTS IN HIGH-LUMINOSITY QUASAR HOSTS AND IMPLICATIONS FOR THE AGN BLACK HOLE MASS SCALE [PDF]
We present new stellar velocity dispersion measurements for four luminous quasars with the Near-Infrared Integral Field Spectrometer instrument and the ALTAIR laser guide star adaptive optics system on the Gemini North 8 m telescope.
C. Grier +9 more
semanticscholar +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Formation and evolution of interstellar filaments: hints from velocity dispersion measurements [PDF]
We investigate the gas velocity dispersions of a sample of filaments recently detected as part of the Herschel Gould Belt Survey in the IC 5146, Aquila, and Polaris interstellar clouds.
D. Arzoumanian +3 more
semanticscholar +1 more source
On the Origin of the Variety of Velocity Dispersion Profiles of Galaxies
Observed and simulated galaxies exhibit a significant variation in their velocity dispersion profiles. We examine the inner and outer slopes of stellar velocity dispersion profiles using integral field spectroscopy data from two surveys, SAMI (for z < 0 ...
San Han +10 more
doaj +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
THE VELOCITY DISPERSION PROFILE OF NGC 6388 FROM RESOLVED-STAR SPECTROSCOPY: NO EVIDENCE OF A CENTRAL CUSP AND NEW CONSTRAINTS ON THE BLACK HOLE MASS [PDF]
By combining high spatial resolution and wide-field spectroscopy performed, respectively, with SINFONI and FLAMES at the ESO/VLT we measured the radial velocities of more than 600 stars in the direction of NGC 6388, a Galactic globular cluster which is ...
B. Lanzoni +9 more
semanticscholar +1 more source
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
Canceling and inverting normal and anomalous group-velocity dispersion using space-time wave packets [PDF]
Layton A. Hall, Ayman F. Abouraddy
openalex +1 more source
Modelling mass distribution in elliptical galaxies: mass profiles and their correlation with velocity dispersion profiles [PDF]
We assemble a statistical set of global mass models for ~2,000 nearly spherical SDSS galaxies at a mean redshift of 0.12 based on their aperture velocity dispersions and newly derived luminosity profiles in conjunction with published velocity dispersion ...
K. Chae, M. Bernardi, A. Kravtsov
semanticscholar +1 more source

