Results 81 to 90 of about 547,861 (372)

Re-visiting the relations: Galactic thin disc age-velocity dispersion relation [PDF]

open access: yes, 2007
The velocity dispersion of stars in the solar neighbourhood thin disc increases with time after star formation. Nordstrom et al. (2004) is the most recent observational attempt to constrain the age-velocity dispersion relation.
Alonso   +73 more
core   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri   +2 more
wiley   +1 more source

IN-SYNC II: Virial Stars from Sub-Virial Cores -- The Velocity Dispersion of Embedded Pre-Main-Sequence Stars in NGC 1333 [PDF]

open access: yes, 2014
The initial velocity dispersion of newborn stars is a major unconstrained aspect of star formation theory. Using near-infrared spectra obtained with the APOGEE spectrograph, we show that the velocity dispersion of young (1-2 Myr) stars in NGC 1333 is 0.92+/-0.12 km/s after correcting for measurement uncertainties and the effect of binaries.
arxiv   +1 more source

Automatic Single Droplet Generator with Control over Droplet Size and Detachment Frequency

open access: yesColloids and Interfaces, 2019
This paper presents a quite simple, fully automatized single droplet generator, which can be an alternative for more expensive and complicated microfluidic devices. The simple generation nozzle connected to the pressure cells and cheap peristaltic pumps,
Dorota Gawel, Jan Zawala
doaj   +1 more source

The black hole mass versus velocity dispersion relation in QSOs/Active Galactic Nuclei: observational appearance and black hole growth

open access: yes, 2004
Studies of massive black holes (BHs) in nearby galactic centers have revealed a tight correlation between BH mass and galactic velocity dispersion.
Kormendy J.   +5 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Numerical Simulation of Pollutant Channeling between Adjacent Road Tunnels [PDF]

open access: yesE3S Web of Conferences
With the development of highway tunnels, the increasing number of continuous tunnels has brought forth a growing concern regarding the dispersion of pollutants between tunnel entrances.
Tang Sha, Han Xiaoyang, Zhi Yansheng
doaj   +1 more source

Testing Newtonian gravity with distant globular clusters: NGC1851 and NGC1904

open access: yes, 2010
Globular clusters are useful to test the validity of Newtonian dynamics in the low acceleration regime typical of galaxies, without the complications of non-baryonic dark matter. Specifically, in absence of disturbing effects, e.g.
Begeman   +25 more
core   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

open access: yesFEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones   +2 more
wiley   +1 more source

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