Results 21 to 30 of about 2,141,111 (233)
Wave telescope technique for MMS magnetometer
Geophysical Research Letters, 2016 Multipoint measurements are a powerful method in studying wavefields in space plasmas. The wave telescope technique is tested against magnetic field fluctuations in the terrestrial magnetosheath measured by the four Magnetospheric Multiscale (MMS ...
Y. Narita +20 more
doaj +1 more source
Научный вестник МГТУ ГА, 2019 In order to simulate the process of design development in full on computer models, including virtual tests of the synthetic aperture radar on an air carrier in model media, the study develops a structural scheme of the conceptual design of the synthetic ...
R. N. Akinshin +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
General Euler Diagram Generation [PDF]
, 2008 Euler diagrams are a natural method of representing set-theoretic data and have been employed in diverse areas such as Visualizing statistical data, as a basis for diagrammatic logics and for displaying the results of database search queries.
Andrew Fish +6 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Jixie chuandong, 2018 The rotation direction and speed of each element in the planetary gear mechanism can be directly shown by drawing the linear velocity vector diagram of the gear ring,planet carrier and sun wheel in the CR-CR planetary gear mechanism.
Liu Chenfu, Zhang Yushu, Qin Yongjie
doaj
, 2020 The purpose of the study was to assess the function of fibres of the left ventricle (LV) and its dynamics after revascularization in patients with non Q myocardial infarction using standard Echocardiography (EchoCG) and Velocity Vector Imaging (VVI ...
A. Yu. Vasilyev +3 more
core +1 more source