Results 11 to 20 of about 44,168 (180)

Travertine crystal growth ripples record the hydraulic history of ancient Rome’s Anio Novus aqueduct

Scientific Reports, 2022
Travertine crystal growth ripples are used to reconstruct the early hydraulic history of the Anio Novus aqueduct of ancient Rome. These crystalline morphologies deposited within the aqueduct channel record the hydraulic history of gravity-driven ...
Duncan Keenan-Jones, Davide Motta, Marcelo H. Garcia, Mayandi Sivaguru, Mauricio Perillo, Ryan K. Shosted, Bruce W. Fouke   +6 more
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Ahora nos ven

Cuadernos de Antropología Social, 2022
En este artículo analizamos algunas obras artísticas exhibidas y producidas en el marco de dos eventos públicos que tuvieron como objetivo recordar el incendio de interfase urbano-forestal del 9 de marzo de 2021 en el noroeste del Chubut.
María Alma Tozzini, Juan Mauricio Lobba Araujo   +1 more
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Spatial and temporal patterns of drought in the Continental U.S. during the past century

Geophysical Research Letters, 2016
This study investigates the spatial and temporal patterns of multiple drought characteristics (duration, severity, and intensity) under different return periods during 1900–2012 in the Continental U.S. (CONUS). We find two significant patterns: Pattern I
Yan Ge, Tushar Apurv, Ximing Cai
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Repressing HIF-1α-induced HDAC9 contributes to the synergistic effect of venetoclax and MENIN inhibitor in KMT2Ar AML

Biomarker Research, 2023
KMT2A-rearranged acute myeloid leukemia (KMT2Ar-AML) is an aggressive subtype of AML with poor response and prognosis. KMT2Ar-AML has been demonstrated to be sensitive to BCL2 inhibitor venetoclax (VEN), but these patients are unable to benefit from ...
Qing Ling, Yutong Zhou, Yu Qian, Jiejing Qian, Yi Zhang, Jinghan Wang, Yanan Zhu, Yile Zhou, Juying Wei, Chunmei Yang, Jie Sun, Wenjuan Yu, Jie Jin, Xiang Zhang   +13 more
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Climatic and terrestrial storage control on evapotranspiration temporal variability: Analysis of river basins around the world

Geophysical Research Letters, 2016
Knowledge of the temporal variability of evapotranspiration (ET) is fundamental to a comprehensive understanding of hydroclimatologic processes under a changing climate and anthropogenic interferences.
Ruijie Zeng, Ximing Cai
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Venetoclax plus bendamustine-rituximab or bendamustine-obinutuzumab in chronic lymphocytic leukemia: final results of a phase Ib study (GO28440)

Haematologica, 2020
Venetoclax (Ven), an orally administered, potent BCL-2 inhibitor, has demonstrated efficacy in chronic lymphocytic leukemia (CLL) in combination with rituximab (R) or obinutuzumab (G). Our aim was to investigate the addition of bendamustine (B) to these
Stephan Stilgenbauer, Franck Morschhauser, Clemens-Martin Wendtner, Guillaume Cartron, Michael Hallek, Barbara Eichhorst, Mark F. Kozloff, Thomas Giever, Gerard Lozanski, Yanwen Jiang, Huang Huang, Daniela Soriano Pignataro, William Schary, Kathryn Humphrey, Mehrdad Mobasher, Gilles Salles   +15 more
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Not BCL2 mutation but dominant mutation conversation contributed to acquired venetoclax resistance in acute myeloid leukemia

Biomarker Research, 2021
Venetoclax (VEN) plus azacitidine has become the first-line therapy for elderly patients with acute myeloid leukemia (AML), and has a complete remission (CR) plus CR with incomplete recovery of hemogram rate of ≥70%.
Xiang Zhang, Jiejing Qian, Huafeng Wang, Yungui Wang, Yi Zhang, Pengxu Qian, Yinjun Lou, Jie Jin, Honghu Zhu   +8 more
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Hydropower versus irrigation—an analysis of global patterns

Environmental Research Letters, 2017
Numerous reservoirs around the world provide multiple flow regulation functions; key among these are hydroelectricity production and water releases for irrigation.
Ruijie Zeng, Ximing Cai, Claudia Ringler, Tingju Zhu   +3 more
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A retrospective comparison of salvage intensive chemotherapy venetoclax-combined regimen in patients with relapsed/refractory acute myeloid leukemia (AML)

Therapeutic Advances in Hematology, 2022
Background: Evidence that a venetoclax (VEN)-combined regimen is effective in relapsed/refractory acute myeloid leukemia (R/R AML) is emerging. However, it is unknown how VEN-combined low intensity treatment compares to intensive chemotherapy (IC) in ...
Silvia Park, Daehun Kwag, Tong Yoon Kim, Jong Hyuk Lee, Joon yeop Lee, Gi June Min, Sung Soo Park, Seung-Ah Yahng, Young-Woo Jeon, Seung-Hwan Shin, Jae-Ho Yoon, Sung-Eun Lee, Byung Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Chang-Ki Min, Seok-Goo Cho, Jong Wook Lee, Hee-Je Kim   +19 more
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Identification of a venetoclax-resistance prognostic signature base on 6-senescence genes and its clinical significance for acute myeloid leukemia

Frontiers in Oncology, 2023
BackgroundSatisfactory responses can be obtained for acute myeloid leukemia (AML) treated by Venetoclax (VEN)-based therapy. However, there are still quite a few AML patients (AMLs) resistant to VEN, and it is critical to understand whether VEN ...
Peng Ke, Peng Ke, Jundan Xie, Jundan Xie, Ting Xu, Ting Xu, Meiyu Chen, Meiyu Chen, Yusha Guo, Yusha Guo, Ying Wang, Ying Wang, Huiying Qiu, Huiying Qiu, Depei Wu, Depei Wu, Zhao Zeng, Zhao Zeng, Suning Chen, Suning Chen, Xiebing Bao, Xiebing Bao   +21 more
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