Results 111 to 120 of about 77,286 (264)

Pulmonary artery catheters or central venous catheters for cardiac surgery: the PUMA Pilot randomised clinical trial

open access: yesAnaesthesia, EarlyView.
Summary Introduction Pulmonary artery catheters are used widely in cardiac surgery despite observed associations with worse outcomes and guidelines that recommend against their routine use. No adequately powered randomised trials are available. Methods The PUMA Pilot was a multicentre, randomised, parallel assignment, open‐label, pilot and feasibility ...
Luke A. Perry   +22 more
wiley   +1 more source

Inferior vena cava obstruction secondary to hepatic alveolar echinococcosis: a case report

open access: yesEgyptian Liver Journal
Hepatic echinococcosis is a global zoonotic disease that typically manifests through direct invasion of the bile ducts and vascular structures of the liver, subsequently spreading to adjacent organs and tissues. Inferior vena cava syndrome resulting from
Jingxin Yan
doaj   +1 more source

The use of rivaroxaban in deep venous thrombosis associated with vena cava inferior agenesis. [PDF]

open access: yesTurk Gogus Kalp Damar Cerrahisi Derg, 2019
Arıkan AA, Emre S, Avni BF.
europepmc   +1 more source

Online Andrology: Real‐World Status Quo of Patients’ Online Information Sources and Comparison With Large Language Models in Germany

open access: yesAndrology, EarlyView.
ABSTRACT Background The internet, including websites and large language models (LLMs), is an increasingly important information resource for medical patients. However, information quality varies, potentially leading to misinformation. Andrological patients may particularly rely on online sources due to the sensitive nature of their conditions ...
Traeger Max   +7 more
wiley   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah   +7 more
wiley   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi   +9 more
wiley   +1 more source

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

open access: yes
Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova   +13 more
wiley   +1 more source

Advances and Challenges in the Multidisciplinary Treatment of Retroperitoneal Infantile Fibrosarcoma in Early Life

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background and Aims Retroperitoneal Infantile Fibrosarcoma (RIFS) is a rare, locally aggressive pediatric soft tissue tumor. Its retroperitoneal location poses challenges due to proximity and potential invasion of critical structures such as the inferior vena cava (IVC).
Gaia Brunetti   +8 more
wiley   +1 more source

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