Results 141 to 150 of about 77,429 (217)

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

open access: yesEuropean Journal of Haematology, Volume 117, Issue 3, Page 533-542, September 2026.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi   +9 more
wiley   +1 more source

Advances and Challenges in the Multidisciplinary Treatment of Retroperitoneal Infantile Fibrosarcoma in Early Life

open access: yesEuropean Journal of Haematology, Volume 117, Issue 3, Page 548-555, September 2026.
ABSTRACT Background and Aims Retroperitoneal Infantile Fibrosarcoma (RIFS) is a rare, locally aggressive pediatric soft tissue tumor. Its retroperitoneal location poses challenges due to proximity and potential invasion of critical structures such as the inferior vena cava (IVC).
Gaia Brunetti   +8 more
wiley   +1 more source

On the History of Hepatic Vein Catheterization

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen   +2 more
wiley   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza   +6 more
wiley   +1 more source

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