Results 181 to 190 of about 117,246 (292)

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Neoadjuvant Glucocorticoids Facilitate Resection in Advanced B‐Type Thymomas: A Propensity‐Matched Analysis of Surgical and Survival Outcomes

open access: yesThoracic Cancer, Volume 17, Issue 1, January 2026.
Neoadjuvant glucocorticoids facilitated less invasive and more complete resection of advanced B‐type thymomas, leading to reduced operative morbidity and improved progression‐free survival compared to upfront surgery. This study supports a novel downstaging strategy for this challenging disease.
Zhen Yu   +7 more
wiley   +1 more source

Patient‐Controlled Sedation in Port Implantation (PACSPI 2)—A Randomised Clinical Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 1, January 2026.
ABSTRACT Optimising pain management during subcutaneous venous port (SVP) implantation is essential for patient‐centred cancer care. However, evidence‐based approaches to minimise intraoperative pain remain underexplored. This trial evaluated the clinical effectiveness and safety of the propofol‐alfentanil patient‐controlled sedation (PCS) technique as
Stefanie Seifert   +5 more
wiley   +1 more source

Urgent radiotherapy for superior vena cava syndrome in metastatic non-small cell lung cancer: a case report. [PDF]

open access: yesTech Innov Patient Support Radiat Oncol
Patel A   +7 more
europepmc   +1 more source

Evaluation of Two High‐Power Ablation Approaches in the Management of Typical Atrial Flutter: A Retrospective Study

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
To compare the acute and long‐term outcomes of high‐power ablation for typical atrial flutter using a 4‐mm irrigated catheter (4‐IC) versus an 8‐mm non‐irrigated catheter (8‐NIC). We conducted a retrospective cohort study of 215 patients who underwent cavotricuspid isthmus (CTI) ablation between January 2019 and December 2024.
Hina Pervaiz   +5 more
wiley   +1 more source

Chest Port Placement in Freestanding Outpatient Vascular Access Centers. [PDF]

open access: yesCureus
Gray RJ   +5 more
europepmc   +1 more source

Mass Spectrometric Measurements of 11‐Deoxycortisol, Androstenedione and Dehydroepiandrosterone Are Superior to Cortisol to Assess Selectivity of Non‐Stimulated Adrenal Vein Sampling

open access: yesClinical Endocrinology, Volume 104, Issue 1, Page 10-18, January 2026.
ABSTRACT Objective Successful adrenal venous sampling (AVS) is traditionally assessed using the ratio of cortisol in adrenal to peripheral venous plasma to calculate the selectivity index. With mass spectrometry other steroids can be simultaneously measured that may improve numbers of apparent successful sampling procedures.
Francesco Alessi   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy