Results 141 to 150 of about 88,268 (304)

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah   +7 more
wiley   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi   +9 more
wiley   +1 more source

Inferior Vena Cava Filter Insertion

open access: yes, 2016
This section provides a comprehensive procedural report for inferior vena cava filter insertion procedure with up-to-date explanatory notes, synopsis of the indications, and contraindications and potential complications in an organized and practical ...
Taslakian, Bedros, Bedros Taslakian
core   +1 more source

Advances and Challenges in the Multidisciplinary Treatment of Retroperitoneal Infantile Fibrosarcoma in Early Life

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background and Aims Retroperitoneal Infantile Fibrosarcoma (RIFS) is a rare, locally aggressive pediatric soft tissue tumor. Its retroperitoneal location poses challenges due to proximity and potential invasion of critical structures such as the inferior vena cava (IVC).
Gaia Brunetti   +8 more
wiley   +1 more source

Leiomyosarcoma of the inferior vena cava [PDF]

open access: yes, 2016
Inferior vena cava leiomyosarcoma is a rare tumor with a variety of symptoms. A 41-year-old woman was admitted with nonspecific epigastric pain. Computed tomography revealed a dense mass between the inferior vena cava and the liver. The patient underwent
Moazeni-Bistgani, M., Basravi, M.
core  

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

open access: yes
Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova   +13 more
wiley   +1 more source

Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Optimizing fluid and nutritional management is a cornerstone of care for children with end‐stage kidney disease on dialysis. Inaccurate assessment of hydration status contributes to hypertension, fluid overload, and increased cardiovascular risk, while masking important changes in muscle and fat compartments that affect growth and ...
Marisa Juarez‐Calderon   +2 more
wiley   +1 more source

Inferior vena cava filters: a concise review.

open access: yes, 2011
Venous thromboembolic disease is associated with significant morbidity and mortality. Anticoagulation has been the mainstay of treatment and prevention. Unfortunately, anticoagulation frequently fails or is contraindicated.
Sahni, Adarsh, Lem, Vincent
core  

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